Gram Positive

Question 1

Corynebacteria diphtheriae- SX

Answer 1

• Tonsillopharyngeal diphtheria- gray-white pharyngeal membranem hoarseness, sore throat & LOW fever
• Laryngotracheobronchial diphtheria- hoarsness, stridor, respiratory distress
• Nasal diphtheria (infants & young) profuse, mucoid grayish discharge

** ALL can lead to myocariditis, renal effects, polyneuritis

Question 2

Corynebacteria diphtheriae- TX

Answer 2

Erythromycin + diphtheria antitoxin

o After recovery- diphtheria toxoid

Question 3

Bacillus anthracis SX & TX

Answer 3

SX:
Cutaneous- painless papule--> painless ulcer--> painless black eschar w/ induration & swelling 
TX:
 Cutaneous- PCN G or quinolone 
 Prophylaxis- Cipro 30-60 days

Question 4

Bacillus cereus

Answer 4

SX- gastroenteritis (ass w/ fried rice)
TX IV related inf & contact lens wearers
- Vanco

Question 5

Clostridium perfringes

Answer 5

SX
 - food poisoning 2nd meat
 - cellulitis & gas gangrene 
TX
 - PCN
    - Allergy- Tetracycline/Clinda