Haematology 🅾️ Flashcards

1
Q

what is hodgkin’s lymphoma

A

a malignant proliferation of lymphocytes characterised by the presence of the Reed-Sternberg cell

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2
Q

clinical features of Hodgkin’s lymphoma

A

typically presents in young adults with cervical or supraclavicular non-tender lymphadenopathy

alcohol-induced pain in lymph nodes

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3
Q

inherited antithrombin III deficiency typical presentation

A

venous thromboembolism in early childhood and a significant family history

generally have heparin resistance

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4
Q

role of antithrombin III

A

inactivates factor IIa, Xa, IXa, XIa

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5
Q

protein C deficiency

A

protein C is responsible for inactivating factors V and VIII
therefore increased risk of thrombosis

the less common thrombophilia but has an association with warfarin initiation so if that is in the Q its more likely to be this

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