Haematology

Question 1

Pregnant patient - Fatigue, pallor, exertional dyspnoea, mouth ulcers

Answer 1

Iron deficiency anaemia

RF - Pregnancy, heavy periods, vegan diet, malabsorption disorders - coeliac

• Koilonychia
• Glossitis
• PICA (craves non food items)

Question 2

Episodic jaundice, dark urine, fatigue, pallor, had some fava beans

Answer 2

G6PD deficiency

(Common in places with malaria)

(Jaundice + dark urine due to increased haemolysis)

Question 3

Fatigue, pallor, bone pain, sob, chest pain

Answer 3

Sickle cell anaemia

(Common in africa)

• Acute chest crises (vaso-occlusion)
• Possible visual symptoms
  Jaundice - due to haemolysis

Question 4

fatigue, pallor, mouth ulcers, paraesthesia

Answer 4

B12 deficiency anaemia

• PERNICIOUS anaemia

RF
- Vegan
- Pregnant
- Malnutrition conditions (coeliac)
- (Possible family history of autoimmune disease)

Question 5

A pregnant woman with fatigue, pallor, mouth ulcers and swollen tongue

Answer 5

Folate deficiency anaemia

Question 6

Fatigue, bruising, recurrent infections, weight loss

Answer 6

Leukaemia

AML, CML

ALL + CLL - will also have lymphadenopathy

Question 7

Painless lymphadenopathy, fever, night sweats, weight loss

Answer 7

Lymphoma

B symptoms

Lymphadenopathy could be painful after alcohol in hodgkin’s lymphoma

Hodgkin’s lymphoma - history of EBV (Glandular fever)

Question 8

Bone pain, fatigue, passing urine more frequently, calcified nodules on knuckles

Answer 8

Multiple myeloma

• Polydipsia

Question 9

Headache, dizziness, itching (worse after hot shower), reddish complexion

Answer 9

Polycythaemia vera

Additional Sx
- Erythromelalgia –> painful burning of hands, toes, palms

(RF - budd chiari syndrome)