Haematology Flashcards
(7 cards)
1
Q
Side effect of the anthracycline: doxorubicin?
A
Cardiotoxicity (acute arrythmia or cardiomyopathy)
this is irreversible
Tissue necrosis
2
Q
Side effects of the antimetabolites / pyrimadine antagonists: capcitabine and 5-FU?
A
Coronary vasospasm
Hand-foot syndrome
Fatal in DMD deficiency
3
Q
Side effects of the antimetabolites / pyrimadine antagonists: gemcitabine?
A
Pulmonary toxicity
Secondary TMA
4
Q
Side effects of platinum agents?
(carboplatin, cisplatin, oxaliplatin)
A
Neurotoxicity
Ototoxicity
Nephrotoxicity
Cold dysasthaesias
5
Q
Side effect of bleomycin?
A
Pulmonary toxicity
6
Q
Side effect of taxanes (docetaxel, pacitaxel)?
A
Peripheral neuropathy
Hypersensitivity
7
Q
What are the side effects of vinka alkyloids (vincristine)?
A
Neurotoxicity
Extravasation injury
