HEMA LEC MOD 2 Flashcards
Erythrocytes have ___, homogenous _____ with a ____ paler than the periphery
circular, biconcave disk, central pallor
Central pallor occupies approximately __ (__ - __micrometers)
1/3, 2-3 micrometers
RBC size:
__ - __ micrometer in diameter
__ - __ micrometer in thickness
__ - __ femtoliter in volume
7 - 8 micrometers
1.5 - 2.5 micrometers
80 - 100 femtoliters
Cell that is <80 femtoliters
microcyte
Cell that is >100 femtoliters
macrocyte
Cell that is within 80 - 100 femtoliters
normocyte / normocytic
Example of hyperchromic RBC
Spherocytes
Staining characteristics:
____ in wet, unstained preparation
Greenish
Staining Characteristics:
___ in Wright’s Stain
Salmon Pink
Young RBCs are flexible and highly deformable?
True or False
True
What do you call old RBCs?
Senescent
Sequestration of RBCs happens in ___
Spleen
How many days will it take to produce mature RBC from BFU-E?
21 days
BFU-E to CFU-E : __ week/s
1 week
CFU-E to Pronormoblast : __ week/s
1 week
How many cell divisions happen before maturing to Pronormoblast?
3 - 5 cell divisions
__ - __ days proliferation & maturation of precursors
6 - 7 days
__ - __ days reticulocyte maturation
2 - 3 days
Reticulocytes:
__ - __ days in BM
1 - 2 days
Reticulocytes:
__ day/s in the circulation
1
What organ removes remnants and polish the RBC to become concave?
Spleen
__ - __ RBCs produced from a single pronormoblast?
8 - 32 RBCs
Life span of mature RBCs
80 - 120 days
1 normoblast is equal to __ - __ RBCSs
8 - 32 RBCs
1 normoblast is equal to __ - __ reticulocytes
16
____ and ____ have the highest RNA content
pronormoblast and basophilic normoblast
Stage where there is a decline in RNA content as Hb increases
a. Polychromatophilic normoblasts
b. Pronormoblast
c. basophilic normoblast
d. Reticulocyte
a. Polychromatic normoblast
__ or __ mitotic divisions in 3 days
3 or 4
Reticulocytes remain in stroma for __ - __ days
1 - 2 days
synthesize Hb in __ - __ days in the marrow and __ day/s in the peripheral blood
1 -2 days, 1 day
Name 2 supravital stains
New Methylene Blue
Brilliant Cresyl Blue
Reticulocyte is described as ___ ___ when viewed in microscope?
Lumpy potato
Type of Erythropoiesis where red cells produced in the BM reaches the circulation and reaches its maturity
Effective Erythropoiesis
Type of Erythropoiesis where red cell that are produced in BM does not reach the circulation and its lifespan
Ineffective erythropoiesis
____ ____ is the abnormal maturation of erythroid precursors forming megaloblasts
megoblastic maturation
Karyorrhexis and Howell-Jolly bodies are characteristic of ___ maturatuon
Megaloblastic Maturation
Has the impaired ability of cell to synthesize DNA and has enlarged cells with nuclear maturation lagging behind cytoplasmic maturation
Megaloblastic Maturation
Normoblastic Nomenclature System is commonly used in ____
United States
Erythroblastic Nomenclature System is commonly used in ____
Europe