HEMA1

Question 1

Anemia can be caused by:

Answer 1

BOTH

Question 2

A classification of anemia wherein the MCV is
greater than 96ft. MCHC is normal

Answer 2

MACROCYTIC NORMOCHROMIC ANEMIA

Question 3

Impaired release of storage iron associated with increased HEPCIDIN levels is due to:

Answer 3

IRON DEFICEINCY

Question 4

Caused by blocks on the protoporphyrin pathway resulting in defective hemoglobin synthesis and iron overload:

Answer 4

SIDEROBLASTIC ANEMIA

Question 5

An anemia with normocytic/normochromic
anemia with characteristic course basophilic
slipping:

Answer 5

LEAD POISONING

Question 6

A falsely elevated HCT is obtained. Which of the
following calculated values will not be affected?

Answer 6

MCH

Question 7

Which of these types of anemia are under the
category of impaired production?

Answer 7

ALL OF
THESE

Question 8

SITUATION: RBC indices obtained on a patient
are as follows: MCV 88um3 fL; MCH 30pg; MCHC 34% (340). The RBCs on the peripheral smear would appear.

Answer 8

NORMOCYTIC, NORMOCHROMIC

Question 9

In an uncomplicated case of severe iron
deficiency anemia, which of the following sets
represents the typical pattern of results?

Answer 9

C

Question 10

What is the first type of cell produced by the
developing embryo?

Answer 10

ERYTHROCYTE

Question 11

As most blood cell lines mature, which of the
following is characteristics?

Answer 11

NUCLEUS TO CYTOPLASM RATION (N:C) DECREASES

Question 12

The direct antiglobulin test is often positive in:

Answer 12

ACQUIRED HEMOLYTIC ANEMIA

Question 13

The anemia of chronic infection is characterized by:

Answer 13

DECREASED SERUM IRON LEVELS

Question 14

A patient is admitted with a history of chronic
bleeding secondary to peptic ulcer. Hematology
workup reveals a sever microcytic, hypochromic
anemia. Iron studies were requested. Which of
the following would be expected in this case?

Answer 14

RESULT C

Question 15

Which of the following sets of laboratory findings is consistent with hemolytic anemia?

Answer 15

DECREASE ERYTHROCYTE SURVIVAL;
INCREASED CATABOLISM OF HEME

Question 16

Chronic blood loss can lead to:

Answer 16

IRON
DIFICIENCY

Question 17

Many micro-spherocytes, schistocytes and
budding off of spherocytes can be seen on
peripheral blood smear of patients with:

Answer 17

EXTENSIVE BURNS

Question 18

Abetalipoproteinemia is characterized by mild
anemia and numerous____ on the peripheral
blood smear

Answer 18

ACANTHOCYTES

Question 19

What is the most common cause of iron
deficiency?

Answer 19

BLEEDING

Question 20

Ineffective erythropoiesis is/are due to the
following, EXCEPT:

Answer 20

IRON DEFICIENCY

Question 21

This red cell parameter is increased in iron
deficiency anemia:

Answer 21

TIBC

Question 22

When there is defective G6PD in red cells, then
the cause of hemolysis is:

Answer 22

INTRINSIC

Question 23

In chronic post-hemorrhagic anemia, this is NOT TRUE.

Answer 23

RETICULOCYTE COUNT IS VERY
LOW

Question 24

Isoimmune hemolytic disease of the newborn
maybe due to:

Answer 24

ABO INCOMPATIBILITY

Question 25

In aplastic anemias, marrow cellularity is:

Answer 25

DECREASED

Question 26

Rh null disease person shows morphological changes in red cells. Persons with Rh-negative condition possesses the CDE antigen:

Answer 26

1ST STATEMENT IS TRUE; 2ND STATEMENT IS NOT TRUE

Question 27

Acanthocytes and echinocytes can be differentiated based on which of the following:

Answer 27

ALL OF THESE

Question 28

The opposite of aplastic anemia is:

Answer 28

POLYCYTHEMIA

Question 29

Extrinsic Hemolytic Anemia is caused by:

Answer 29

ALL OF THESE

Question 30

Defect of red cell itself usually hereditary & grouped as membrane, metabolic or hemoglobin defects:

Answer 30

INTRINSIC HEMOLYTIC ANEMIA

Question 31

Anemia most commonly present with which one of the following set of symptoms:

Answer 31

SHORTNESS OF BREATH AND FATIGUE

Question 32

Which one of the following conditions would be included in the differential diagnosis of an anemic adult patient with an MCV of 125fL and an RDW of 20% (reference interval: 11.5% to 14.5%)

Answer 32

VITAMIN 12 DEFICIENCY

Question 33

Schistocytes, ovalocytes, and acanthocytes are examples of abnormal changes in RBC:

Answer 33

SHAPE

Question 34

Which of the following is detectable only by examination of a peripheral blood film? .

Answer 34

POIKILOCYTOSIS

Question 35

Which of the following patients would be considered anemic with a hemoglobin value of 14.5g/dL?

Answer 35

A NEWBORN BOY

Question 36

What are the initial laboratory tests that are performed for the diagnosis of anemia?

Answer 36

CBC, RETICULOCYTE COUNT, AND PERIPHERAL BLOOD FILM EXAMINATION

Question 37

An increased in which one of the following suggests a shorted life span of RBCs and hemolytic anemia?

Answer 37

RETICULOCYTE COUNT

Question 38

An autoimmune reaction destroys the hematopoietic stem cells in the bone marrow of a young adult patient, and the amount of active bone marrow, including erythroid precursors, is diminished. Erythroid precursor that are present are normal in appearance, but there are too few to meet the demand for circulating red blood cells, and anemia develops. The reticulocyte count is low. The mechanism of the anemia would be described as:

Answer 38

INSUFFICIENT ERYTHROPOIESIS

Question 39

Which of the following are important to consider in the patient’s history when investigating the cause of an anemia?

Answer 39

ALL OF THESE

Question 40

To determine which of the following condition would be included in the differential diagnosis of an anemic adult patient with an absolute reticulocyte count of 20 3 109 /L and an MVC of 65fL

Answer 40

IRON DEFICIENCY