HEMA2

Question 1

It measures the time required to generate
thrombin and fibrin polymers via intrinsic
pathway:

Answer 1

APTT

Question 2

The following are negatively charged particulate
activator used in APTT except:

Answer 2

THROMBIN

Question 3

An increased in APTT will affect the following
coagulation factor, Except:

Answer 3

FVII

Question 4

Determines the rate of thrombin-induced
cleavage of fibrinogen to fibrin monomers and
subsequent polymerization of hydrogen bonded polymers:

Answer 4

TT

Question 5

It is also known as the plasma thromboplastin
antecedent:

Answer 5

FXI

Question 6

It is also known as the plasma thromboplastin
component:

Answer 6

FIX

Question 7

The following coagulation factor are consumed
during the process of coagulation, except

Answer 7

FXII

Question 8

Which of the following coagulation factor is
inhibited by warfarin?

Answer 8

FIX

Question 9

The specimen if a patient with prolong APTT was subjected to a mixing study shows correction of APTT after immediate mixing but no correction after a 2-hour incubation was possibly indicated by:

Answer 9

VIII INHIBITOR

Question 10

This procedure is used to monitor oral
anticoagulant therapy, a screening test in
diagnosis of coagulation deficiencies and a
component of liver profile assessment.

Answer 10

PT

Question 11

It involves the principle of adding of plasma to an excess of extrinsic thromboplastin-calcium
substrate. The following coagulation factor
therefore is being detected by this test, except:

Answer 11

FIX

Question 12

Which of the following coagulation factor is not
consumed during the process of coagulation?

Answer 12

FXI

Question 13

Which of the following coagulation factor will be
most likely affected if the patient has vitamin K
deficiency?

Answer 13

FIX

Question 14

Anti-FVII inhibitor is usually associated with?

Answer 14

BLEEDING

Question 15

This test is used to identify and quantitate
deficiencies in the intrinsic clotting system and
to control anticoagulant therapy:

Answer 15

PTT

Question 16

The following coagulation factor are consumed
during the process of coagulation, except:

Answer 16

PROCONVERTIN

Question 17

The following are calcium and vitamin K
independent coagulation factors, except:

Answer 17

PTC

Question 18

The following are considered as serine proteases, except:

Answer 18

LABILE FACTOR

Question 19

Which of the following will serve as an activator
in prothrombin time test?

Answer 19

NEITHER

Question 20

The following are calcium and vitamin K
dependent coagulation factor, except:

Answer 20

PTA

Question 21

The component of the APTT reagent which will
activate the contact factor in intrinsic pathway:

Answer 21

PF3

Question 22

Which of the following will serve as the source of tissue factor:

Answer 22

BOTH

Question 23

The primary in vivo initiation mechanism for
extrinsic coagulation cascade depends on the
formation of:

Answer 23

TF:VIIa

Question 24

When a person has Vitamin K deficiency, the
following coagulation factor will most likely be
affected, except:

Answer 24

E

Question 25

It is considered the marker of thrombosis and fibrinolysis:

Answer 25

FRAGMENT D-D

Question 26

The component of the APTT reagent which is required to activate the prothrombin in the common pathway:

Answer 26

CALCIUM CLORIDE

Question 27

A subtype of Von Willebrand Disease characterized by mutations within the A1 structural domain of Von Willebrand Factor molecules:

Answer 27

SUBTYPE 2B VON WILLEBRAND DISEASE

Question 28

A subtype of Von Willebrand Disease characterized by an autosomal point mutation in the A2 and D1 structural domains of the Von Willebrand Factor molecules.

Answer 28

SUBTYPE 2A VON WILLEBRAND DISEASE

Question 29

A subtype of von Willebrand Disease characterized by an autosomal VWF gene missense mutation in the D9 domain of the von Willebrand factor molecule.

Answer 29

SUBTYPE 2N VON WILLEBRAND DISEASE

Question 30

A subtype of von Willebrand disease characterized by a qualitative VWF variant that possesses poor platelets receptor binding site generating a normal multimeric distribution pattern in electrophoresis.

Answer 30

SUBTYPE 2M VON WILLEBRAND DISEASE

Question 31

APTT: Prolonged PT: Prolonged Aged Serum: Not Corrected Age Plasma: Not Corrected Adsorbed plasma: Corrected

Answer 31

E

Question 32

APTT: Prolong PT: Prolong Aged Serum: Not Corrected Fresh Serum: Corrected Aged Plasma: Corrected

Answer 32

STUART FACTOR

Question 33

APTT: Prolong PT: Prolong Aged Serum: Not Corrected Fresh Serum: Not Corrected Aged Plasma: Corrected

Answer 33

FIBRINOGEN

Question 34

PTT: Prolong PT: Prolong Adsorbed Plasma: Not corrected Fresh Plasma: Corrected Aged Plasma: Corrected

Answer 34

PROTHROMBIN

Question 35

APTT: Prolong PT: Prolong Fresh Serum: Corrected Aged Serum: Corrected Aged Plasma: Not Corrected

Answer 35

LABILE FACTOR

Question 36

APTT: Prolong PT: Normal Aged Plasma: Corrected Adsorbed Plasma: Corrected Aged Serum: Corrected

Answer 36

E

Question 37

APTT: Prolong PT: Normal Fresh Serum: Not Corrected Aged Plasma: Not Corrected Adsorbed Plasma: Corrected

Answer 37

ANTIHEMOPHILIC FACTOR A

Question 38

APTT: Prolong PT: Normal Adsorbed plasma: Not Corrected Fresh Serum: Corrected Aged Serum: Corrected

Answer 38

PLASMA THROMBOPLASTIN COMPONENT

Question 39

APTT: Prolong PT: Normal Aged Serum: Not Corrected Fresh Plasma: Corrected Adsorbed Plasma: Corrected

Answer 39

ANTIHEMOPHILIC FACTOR A

Question 40

APTT: Prolong PT: Normal Adsorbed plasma: Not Corrected Aged Serum: Corrected Aged Plasma: Corrected

Answer 40

CHRISTMAS FACTOR