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MTAP 2 - FINALS - RATIO > HISTOPATHOLOGY > Flashcards

HISTOPATHOLOGY Flashcards

1
Q

Enzymes used for antigen retrieval in IHC
1. Phosphatase (AP – FOR LABELLING
ANTIBODY)
2. Trypsin
3. Lipase
4. Protease

A

2 & 4 AND PEPSIN

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2
Q

Which of the following statements is incorrect?

A

NONE OF THESE

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3
Q

All of the following are methods of antigen retrieval except:

A

INCINERATOR HEATING

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4
Q

Advantages of enzymatic IHC except:

A

NONE OF
THESE

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5
Q

Sources of polyclonal antibodies
1. Sheep
2. Goat
3. Rabbit
4. Mice

A

MICE

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6
Q

Compatible counterstains for DAB
1. Brilliant green
2. Methyl violet
3. Eosin
4. Safranin

A

NONE OF THESE

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7
Q

If alkaline phosphate was used to label antibodies in IHC which of the following can be used?
1. DAB
2. Fast Red TR salt
3. Amino Ethyl Carbazole
4. BCIP

A

2 & 4

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8
Q

Which of the following chromogens that when used will produce a bluish violet or black violet color?

A

BCIP

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9
Q

In IHC, what is the incubation time and
temperature to link antibody with enzyme?

A

30-60 MINUTES AT RT

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10
Q

Which of the following is the most commonly used enzyme label in IHC?

A

HRP

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11
Q

In IHC, which form of hematoxylin that when used tissue morphology are well defined?

A

HARRIS

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12
Q

Acceptable specimens for IHC except:

A

NONE OF
THESE

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13
Q

Which of the following is an oncofetal antigen that is very useful differentiating mesothelioma and adenocarcinoma.

A

CEA

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14
Q

Which is highly specific for myogenic tumor?

A

DESMIN

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15
Q

Which of the following is the marker for
choriocarcinoma?

A

HCG

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16
Q

The tumor marker that will confirm diagnosis of
astrocytoma?

A

GFAP

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17
Q

An epithelial tumor marker which is also positive in certain pancreatic and salivary gland cancer

A

PSA

18
Q

Conditions that will stan positive for vimentin.

A

ALL OF THESE

19
Q

Which of the following is synthesized by placental syncitioltrophoblast?

A

HCG

20
Q

All are intermediate filament markers except:

A

TTF-1

21
Q

Which of the following is more common in
carcinomas of the colon and stomach?

A

CK 20

22
Q

Which can be helpful in determining tumor site?

A

EMA

23
Q

Most common form of antibody used in IHC?

A

IgG

24
Q

True of IHC except:

A

D. SPECIMEN FOR IHC IS
LIMITED ONLY TO PRICESSED SPECIMEN LIKE
PARAFFIN EMBEDDED TISSUES

25
Q

Uses of this chromogen can lead to production of brick red color.

A

AEC

26
Q

Cells found in cervico vaginal smear with a
diameter of 15-30u

A

PARABASAL CELLS

27
Q

Which cell has basophilic vacuolated cytoplasm.

A

INTERMEDIATE CELLS

28
Q

In Pap’s staining of non-gynecological specimens. Which form of hematoxylin is used as nuclear stain?

A

HARRIS

29
Q

Which of the following are used as counterstains in Pap’s staining?

A

2 & 4

30
Q

Which of the following cells in cervico vaginal
smear is shed in response to ovarian hormone?

A

ENDOMETRIAL CELLS

31
Q

These are boat shaped cells with a tendency to fold or curl on edges.

A

NAVICULAR CELLS

32
Q

Which may assume a “honeycomb” appearance?

A

ENDOCERVICAL CELLS

33
Q

The presence of these cells suggests a combine
estrogen-progesterone effect?

A

NAVICULAR CELLS

34
Q

Predominance of which of the following cells is
noted following childbirth?

A

PARABASAL CELLS

35
Q

These are polygonal squamous cells measuring 45-50um in diameter.

A

SUPERFICIAL CELLS

36
Q

In Pap’s staining of gynecological specimens. Which form of hematoxylin is used as nuclear stain?

A

HARRIS

37
Q

In Pap’s staining of the following will that when
used will stain the cytoplasm of other cells
including non-keratinized squamous cells.

A

LIGHT GREEN SF

38
Q

In cytochemistry, which can be used to stain
glycogen?

A

PERIODIC ACID SCHIFF

39
Q

Which is considered to be that staining method of choice in exfoliative cytology.

A

PAPANICOLAOU

40
Q

All of the following statement are correct except:

A

E. NONE OF THESE

MTAP 2 - FINALS - RATIO (6 decks)

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