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Flashcards in Hematology Deck (33)
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1

Blood cells are referred to as _____ all of which are suspended in _____ fluid.

corpuscles
plasma

2

_____ is plasma without coagulation factors (especially fibrinogen)

Serum

3

Plasma has a higher protein concentration which establishes the _____

Osmotic gradient

4

~60% of plasma protein is _____
~35%of plasma protein are _____

albumin
globulins

5

What are the 3 types of Corpuscles?

Erythrocytes
Leukocytes
Thrombocytes

6

Why do Erythrocytes appear red?

Due to the 200-300 molecules of hemoglobin in each

7

What are the 2 types of hemoglobin?

Type A (adult)
Type F (fetal)

8

What is Myoglobin?

Muscle "hemoglobin"
this is the oxygen store within muscle fibers
its greater oxygen affinity curve allows for transfer of oxygen from blood to muscles

9

_____ is the formation of blood cells (corpuscles)

Hematopoiesis

10

All corpuscles arise from cells known as _____.

Pluripotent uncommitted stem cells

11

_____ is the production of erythrocytes.

Erythropoiesis

12

_____ is a glycoprotein hormone secreted by the Kidneys (90%) and Liver (10%) that increases the rate of production of red blood cells in response to falling levels of oxygen in the tissues.

Erythropoietin

13

_____ anemia is caused by a lack of dietary iron, poor iron absorption or loss of iron stores

Iron-Deficiency

14

_____ anemia is a lack of vitamin B12

Pernicious

15

_____ anemia results from a decrease in blood cell production (radiation, benzene)

Aplastic

16

_____ anemia results from an increase RBC destruction surpassing replacement rate

Hemolytic

17

_____ anemia is a result of blood loss

Hemorrhagic

18

What are the 2 classifications of leukocytes?

Granulocytes
Agranulocytes

19

Granulocytes can be subdivided in to 3 types. What are they?

Neutrophils
Eosinophils
Basophils

20

What are the 2 types of Agranulocytes?

Monocytes
Lymphocytes

21

_____ is the most abundant leukocyte, formed in bone marrow. They contain multi-lobulated nuclei, and efficient in engulfing things.

Neutrophils

22

As neutrophils granules become depleted this causes enzyme and histamine release prior to neutrophil death known as _____.

Neutrophil burst or degranulation

23

Neutrophils pass through capillary and venue pores in a process known as _____.

diapedesis

24

Neutrophils also produce _____ which cause the temperature regulatory center in the hypothalamus to raise body temperature (fever)

pyrogens

25

_____ originate in bone marrow, are motile and slightly phagocytic.

Eosinophils

26

_____ originate in marrow and have little to no phagocytic activity.

Basophil

27

_____ the largest of the leukocytes (about 3X the size of an erythrocyte). Capable of diapedesis, upon migration to tissue called macrophage

Monocytes

28

_____ nucleus is large, round and cell has little cytoplasm. There are T-_____ and B-_____.
(all same word)

Lymphocytes

29

T-lymphocytes complete their development in the _____ and B-lymphocytes mature in the _____.

Thymus gland
Spleen

30

Activated T-lymphocytes give rise to clones of lymphocytes responsive to the antigen, conferring _____

Cell-mediated immunity