Hematology Week 1: Transfusion Medicine Flashcards by Jay Sandoval

Q

Question 1

A

B 17 years old

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Q

Question 2

A

A IgM

IgM is large and can fix complement as well as cause vascular hemolysis

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Q

Question 3

A

D Group AB

because it is plasma

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Q

ABO Blood Groups

A

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Q

ABO Inheritance

A

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Q

Prevalence of ABO Types

A

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Q

Blood Components

A

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Q

Indications for RBC Transfusion

A

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Q

Non emergency Indications for RBC Transfusion

A

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Q

Question 4

A

2 units

because 1 unit of RBCs 1g/dL increase

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Q

RBC Post-transfusion Increment

A

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Q

Plasma

A

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Q

Indications for plasma transfusion

A

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Q

Platelets

A

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Q

Indications for Platelet Transfusion

A

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Q

Platelet dysfunction indications for platelet transfusion

A

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Q

Cryoprecipitate

A

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Q

Cryoprecipitate contents and storage

A

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Q

Indications for Cryoprecipitate

A

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Q

Question 5

A

RBCs

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Q

Question 6

A

B Platelet dysfunction

Bernard-soulier platelet dysfunction

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Q

What is needed to know to safely transfuse?

A

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Q

Question 7

Sarah is O neg

Derek is AB neg

A

No

because her whole blood has anti A and anti B antibodies

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Q

can a group O mom give birth to a AB child

A

NO

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Question 8

D dog

Rh Blood Group

Biggest Clinical concerns of RhD

Required testing for RBC Transfusion

Agglutination reactions

Front type & Back Type of ABO typing

Front type is patient RBCs Back Type is patient plasma

Antibody screen

Antibody screen process

incubate with anti IgG Agglutination rxn is positive

RBC Antibody screen

Antibody screen clinical significance and caveats

Crossmatch

Direct Crossmatch

Direct Antiglobulin test

DAT

DAT indications

How DAT works?

Question 9

D O- blood with AB plasma

Question 10

C A+ blood with A plasma

O- RBC

Emergency Release RBCs

Emergency Release Plasma

HDFN AKA

Hemolytic Disease of the Fetus and Newborn

HDFN

Why is IgG helpful to pass to the fetus?

The second most common cause for HDFN

HDFN PAthogenesis

Prevention of Anti-D HDFN

Question 11

D K antibodies cross the placenta and attack fetal erythroblasts with resultant anemia Actually, attack erythroblasts in the bone marrow and can be very devastating

Leukocyte Reduction

Product Modifications

Leukocyte Reduction

Reduce risk of CMV transmission through transfusion

Leukocyte reduction

Irradiating Blood Products

GVHD Mortality

\>90%

Indications for irradiation

Transfusion take-home points

Question 12

D 100,000

Question 13

C 20-24 \*C 5 days

What is stored at 20-24 \*C for 5 days?

Platelets

What is stored at 1-6 \*C for 5 days?

RBCs

What is stored at -18 \*C for 1 year?

Cryoprecipitate or plasma

Question 14

D Transfusion-associated GVHD Danger of family member transfusion isthat we may not recognize their cells are foreign but theirs might