Hematopoeisis Flashcards Preview

Hematology > Hematopoeisis > Flashcards

Flashcards in Hematopoeisis Deck (13)
Loading flashcards...
0

The pluripotential stem cell is stimulated by: (3)
inhibited by: (1)

Stimulated by:
Phytohemagglutin
Cyclophosphamide
Concanavalin A

Inhibited by:
Hydroxyurea

1

Predominant hemoglobin at birth?

Hgb F

*80%

2

Stage of Granulopoeisis where in synthesis of peroxidase-rich primary granules BEGINS and ENDS.

Promyelocyte

3

Stage of Granulopoeisis that begins to form secondary granules; last stage to undergo mitosis.

Myelocyte

4

Stage of Granulopoeisis also known as Juvenile cell. Kidney/bean/peanut shape.

Metamyelocyte

*indentation of nucleus is

5

Mitotic pool of Granulopoeisis.

Myeloblast -> Myelocyte
DIVIDING STAGES; 2-3 days; 4-5 cell divisions.

Maturation pool:
Metamyelocyte -> mature; 5-7 days; NO DIVISIONS

6

Test for PHAGOCYTOSIS.

1. Boyden Micropore Filter Technique
2. Rebuck Skin Window Technique
3. Nitroblue Tetrazolium Test

7

Eosinophils damage what stage of helminths.

Larval stage

8

Neutrophilia is seen in: (4)

Infection
Inflammation
Malignancy
Lithium toxicity

9

Neutropenia is seen in:

Typhoid fever
Paratyphoid
Brucellosis
Measles
Yellow fever
Infectious hepatitis
Rubella
Neonatal isoimmune neutropenia

10

Decreased in the presence of glucocorticoids.

Eosinophils
Basophils
Monocytes

11

Impaired directional and random motility of phagocytes.

Lazy leukocyte syndrome

*JOB's syndrome-> impaired directional motility ONLY.

12

Site of choice for BONE MARROW preperation and evaluation.

Posterior iliac crest

*collection-> trephine biopsy and aspiration