HIGH YIELD

Question 1

which drug causes a disulfuram-like effect?

Answer 1

metronidazole

Question 2

which GnRH agonist causes suicidal ideation and seizures?

Answer 2

histrelin

Question 3

which drug has a BBW for hepatotoxicity?

Answer 3

flutamide

Question 4

nilutamide has a BBW for what?

Answer 4

Respiratory insufficiency

Question 5

which drug can cause citrate toxicity?

Answer 5

spiuleucel

Question 6

which drug can cause a mineralocorticoid state and is also category X?

Answer 6

abiraterone

Question 7

aromatase inhibitors are metabolized by what CYP enzyme?

Answer 7

CYP19A1 (ROME in 1901)

Question 8

levofloxacin and ofloxacin have a BBW for what?

Answer 8

increased risk of tendonitis & rupture

exacerbation of muscle weakness (avoid with myasthenia gravis)

Question 9

which drug class causes taste disturbance?

Answer 9

levofloxacin & ofloxacin

Question 10

name the anti-protozoal drug that can cause discoloration of the urine?

Answer 10

metronidazole

Question 11

name the antiprotozoal drug that has a risk of secondary malignancies?

Answer 11

metronidazole

Question 12

conazoles inhibit what enzyme

Answer 12

14-alpha demethylase

Question 13

which class of drugs can weaken latex condoms or diaphragms?

Answer 13

conazoles