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STEP1 > HISTOLOGIC DEF > Flashcards

HISTOLOGIC DEF Flashcards

1
Q

Hypercellular Stroma compressing associated ephithelium (Mamary tissue)

A

Fibroadenoma

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2
Q

a mass that increases in size in response to estrogen. As such, enlargement of the mass is often seen during pregnancy, prior to menstruation, or following initiation of combination oral contraceptive pills.
Young Women

A

Fibroadenoma (bening)

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3
Q

high-risk features of cancer

A

necrosis, calcifications

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4
Q

connective tissue and cysts with “leaf-like” lobulations.

A

phyllodes tumor (bening)

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5
Q

Cyst lined by metaplastic apocrine cells

A

Fibrocystic change

  • Most common in premenopausal women
  • Multiple, bilateral, painful breast lumps
  • “Lumpy bumpy” breast masses
  • Symptoms are associated with ↑ estrogen
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6
Q

proliferation of Papillary cells with fibrovascular core

A 
intraductal papilloma (bening)
\+bloody or serosanguineous nipple discharge!!!
Buzzword: straw-color nipple discharge
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7
Q

Small,glandular,duct-like cell with desmoplastic stroma

A

Invasive ductal carcinoma

  • -firm, fibrous, “rock-hard” mass with sharp margins
  • -older woman
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8
Q

Eczematous patches over the nipple and areolar skin

A

Pagett Dx

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9
Q

Shed epithelia within the mucous are described as whorls

A

ASMA

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10
Q

eosinophils infiltrating in the lamina propria, “charcot liden crystals” CON plugs de mucus

A

ASMA

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11
Q

Carbon-laden macrophages

A
  • Coal workers

* ligeramente eb fumadores

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12
Q

*Hypertrophy of goblet cells

A

Bronquitis

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13
Q

Large alveoli associated with loss of septae

A

emphysema

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14
Q

Hypergranulosis is the increased thickness of the stratum granulosum

A

Lichen planous

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15
Q

Separation of epidermal layer (Acantholysis)

A

Pemphigus vulgaris

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16
Q

Epidermal hyperplasia

↑ spinosum layer

A

Acanthosis nigricans

17
Q

↑ stratum corneum

A

Hyperkeratosis

  • Callos
  • Psoriasis
18
Q

↑ stratum granulosum

A

Hypergranulosis

linchen planous

19
Q

Retention of nuclei (Parakeratosis)

Stratum corneum

A

Actinic keratosis

Psoriasis

20
Q

Edematous fluid in intercellular spaces of epidermis

A

Spongiosis

Eczematous dermatitis

21
Q

Lung mass-> Neuroendocrine growth patterns (ie, rosettes)

Centrally or peripherally located, often grows into the lumen of the bronchi

A

Carcinoid Tumor

También crece en el intestino delgado

22
Q

Lung mass-> Epithelial glandular tumor

Peripherally located

A

AdenoCA

23
Q

Lung mass-> Large undifferentiated anaplastic cells, pleomorphic giant cells
Peripherally located

A

Large Cell Carcinoma

  • gynecomastia
  • Galactorrhea (Due to incresed bHcG)
24
Q

Lung mass-> Sheets of round basophilic cells with scant cytoplasm (Kulchitsky cells)
Contains granules, stains positive for chromogranin, synaptophysin, neuron-specific enolase
-Centrally located (“S for central”)

A

SMALL CELL CA

25
Q

Lung Mass-> Stratified squamous cells, keratin pearls, intercellular bridging
Metaplasia (columnar epithelium to squamous)
Gross pathology will show ***central necrosis and cavitation
Centrally located (“S for central”)

A

Squamous cell CA

26
Q

nutmeg liver-> dilated sinusoids surrounding a pale area of normal liver tissue.

A

congestive hepatopathy
*** Diastolic heart failure results in venous congestion due to a backup of blood in the superior and inferior vena cava.

27
Q

tumor ovarico-> tumors are composed of transitional epithelium
coffee bean nuclei

A

Brenner tumor

28
Q

tumor ovarico-> epithelial lesions,Composed of cells resembling the fallopian tube epithelium
Ciliated columnar epithelium

A

Serous Cystadenoma

29
Q

Solid ovarian tumor with Large,dysplastic cells with clear cytoplasm surrounding a central nucleus.

A

Dysgerminomas

30
Q

Chocolate cyst of simple columnar epithelium with tubular glands

A

Endometriosis

31
Q

Tall columnar cells with cellular atypia lining crowed glands (abnormal uterine bleeding)

A

endometrial carcinoma

32
Q

display nuclear enlargement with granulation, koilocytic change, and an increased ratio of nucleus to cytoplasm.

A

Cervical cancer

33
Q

endometrial glands and stroma penetrating the musculature of the uterus. (myometrium)

A

Adenomyosis

34
Q

“Fried egg” cells

A

Germ cell ovarian carcinoma

*10-30 years of age with an adnexal mass, abdominal enlargement, abdominal pain, and abnormal vaginal bleeding

35
Q

Keratin pearls

A

squamous cell carcinomas

STEP1 (19 decks)

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