Histology 2 Flashcards

1
Q

What does the epithelia do?

A

Forms barriers for protection, absorption and secretion

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2
Q

What is the epithelia?

A

Cohesive sheets of cells, with one or more layers, resting on a basement membrane.

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3
Q

Where are epithelia found?

A

‘ On the edges of us’ etc surface of our skin, lining of our mouth, lining of our gut

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4
Q

What are the 7 types of epithelium?

A

Simple squamous
Simple cuboidal
Simple columnar
Microvilli and cilia
Stratified epithelia
Pseudo-stratified epithelia
Cell junctions

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5
Q

What is simple epithelia?

A

Single layer of cells on a
basement membrane

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6
Q

What is stratified (compound) epithelia?

A

Two or more layers of cells on
a basement membrane

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7
Q

What is simple squamous epithelium?

A

Single layer of flattened plate-like cells on a basement membrane

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8
Q

Where are Simple squamous epithelium found?

A

Lines inside of blood vessels (endothelium)
Outside of lungs (mesothelium)
Abdominal organs (peritoneum)

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9
Q

What is the simple cuboidal epithelium?

A

Single layer of cells with similar height and width on a basement membrane

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10
Q

Where is simple cuboidal epithelium found?

A

Line kidney tubules
Small ducts

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11
Q

What is the simple columnar epithelium?

A

Single layer of cells taller than they are wide, on a basement membrane

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12
Q

Where is simple columnar epithelium found?

A

Line the stomach
Intestines
Uterus

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13
Q

What is microvilli?

A

Microscopic projections on luminal surface of absorptive cells

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14
Q

What is the purpose of microvilli?

A

Increase surface area
Intestinal brush border

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15
Q

What is the cilia?

A

Microscopic motile projections on luminal surface of cells

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16
Q

Where are cilia found?

A

Respiratory tract
Reproductive tract

17
Q

What are features of the stratified epithelia?

A

Protective function
Many layers of cells
Continually being worn down
Worn-away cells replaced from below

18
Q

What are the locations of stratified epithelia?

A

Found at sites subject to abrasive forces

19
Q

What is the stratified squamous non-keratinising epithelium?

A

Multiple layer of cells on a basement membrane

20
Q

Where are stratified squamous non-keratinising epithelium found?

A

Lines the mouth, oropharynx, oesophagus, vagina

21
Q

What are stratified squamous keratinising epithelium?

A

Multiple layer of cells on a basement membrane

22
Q

Where are stratified squamous keratinising epithelium?

A

Skin

23
Q

What is the pseudostratified epithelium?

A

Single layer of cells of variable height, mimicking multiple layers on a basement membrane

24
Q

Where are pseudostratified epithelium found?

A

Lines the conducting airways

25
Q

What is urothelium?

A

Specialised stratified epithelium

Breaks the rules – looks stratified, probably is stratified, but: Surface layer of umbrella cells

26
Q

What is the basement membrane?

A

Composed of several extra-cellular proteins including Collagen IV and Fibronectin

27
Q

Why is the basement membrane important?

A

Essential for the proper functioning and survival of the epithelium

28
Q

With what stain can base membrane be seen?

A

PAS

29
Q

What are epithelial junctions (occluding, tight junctions)?

A

Band-like fusions between cells that are impervious to most molecules
Prevent diffusion between cells

30
Q

What are epithelial junctions (desmosomes)?

A

Plaques that form physical joins between cells and connect the cytoskeletons of adjacent cells

Spread forces across several cells

31
Q

What are epithelial junctions Gap (aka communicating) junctions?

A

Electrical junctions that permit the transfer of small molecules

Electrically couple adjacent cells

32
Q

Which two proteins are principally involved in the generation of ciliary movement?

A

Tubulin and Dynein

33
Q

A gland secretes by shedding individual cells.
What type of secretion is this?

A

Holocrine

34
Q

What are hemidesmosomes?

A

Multiprotein complex that facilitates adhesion of basal epithelial cells to underlying basement membrane