Histology Flashcards

(81 cards)

1
Q

Cell is how much water?

A

80%

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2
Q

what is the cell membrane made up of and how can it be described?

A

hydrophillic lipid bilayer
anchored membrane proteins
proteins that can laterally diffuse
selectively permeable and amphipathic

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3
Q

what is an inclusion?

A

non bound organelles synthesised by the cell

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4
Q

3 componenets of cytoskeleton

A

Microtubules, intermediate filaments, microfilaments

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5
Q

where do microtubules originate from

A

MTOC, centrosome

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6
Q

what are microtubules made of

A

2 tubulin strands, alpha and beta tubulin

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7
Q

name of transport molecules that attach to microtubules

A

dynein and kinesin

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8
Q

what are microfilaments made of

A

fine actin strands

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9
Q

what binds intracellular elements together

A

intermediate microfilaments

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10
Q

heterochromatin

A

highly condensed DNA

not undergoing transcription

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11
Q

euchromatin

A

less condensed DNA undergoing transcription

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12
Q

What does the ER do?

A

membrane bound spaces
SER - processes popypeptides
RER - involved in protein synthesis, ribosome rich and provides space for polypeptide

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13
Q

Name of inner mitochondrial membrane and its folds?

A

Christae

increase SA

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14
Q

tight junction?

A

prevents diffusion

also called occluding

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15
Q

anchoring junctions?

A

links cells togehter by actin molecules

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16
Q

desmosomes?

A

sub membrane intermediate filaments of adjacent cells.

skin for mechanical stability

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17
Q

gap junction

A

allows selective diffusion through connexon pores

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18
Q

why do cardiac muscle cells require gap junctions

A

to allow for a wave of excitation to occur

not required in skeletal muscle

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19
Q

H&E?

A

Haematoxylin (purple and acidic affinity) and eosin (pink and basic affinity)

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20
Q

How is a slide prepared?

A

sliced thinly, dehydrated, put into organic solvent, penetrated in hot wax.
wax washed out and cut on microtome.
stained

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21
Q

What is an artifact

A

a distortion when preserving a tissue

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22
Q

4 basic tissue types

A

Epithelium, connective, nervous, muscle

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23
Q

At apical and basal ends epithelial cells are

A

polar

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24
Q

epithelial cells attached to

A

basal lamina

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25
Squamous
flattened like shape
26
cuboidal
cube shaped
27
columnar
column shaped
28
simple epithelium
single layer
29
stratified epithelium
multi layered
30
pseudostratified epithelium
appears single layered but actually all attached to basal lamina
31
what is a goblet cell
a cell that secreted mucous | it acts as its own gland
32
endocrine gland
secreted into vascular system from basal end
33
exocrine gland
secreted into duct or tissue from apical end
34
examples of soft tissue
tendons, ligaments, dermis of skin
35
types of cartilage
elastic, fibrocartilage, hyaline
36
where does hard connective tissue receive its nutrients
extracellular matrix
37
what are the types of bone
diaphysis (hard) epiphysis (softer)
38
what is the extracellular matrix made of
ground substance - GAGs fibres tissue fluid
39
what are fibroblasts
maintain extracellular matrix
40
fat cell?
adipose
41
types of muscle and funcion
Cardiac - walls of heart, not very striated. contains intercalated disk skeletal - conscious control, striated and multinucleated smooth - involuntary and lines hollow organs - no striations
42
types of neuron
multipolar bipolar pseudounipolar
43
schwann cells?
PNS - support cells and produce myelin
44
bipolar neuron?
one dendrite one axon
45
pseudounipolar neuron?
axon in both directions
46
multipolar neuron?
one axon many dendrites
47
3 glia of CNS
microglia astrocytes oligodenrocytes
48
3 salivary glands
Parotid submandibular sublingual
49
which salivary gland produces most mucous
sublingual
50
True/false: saliva has same salt content to blood
False - it is hypotonic
51
What structural tissues compose the GI tract?
Mucosal layer - epithelium with basal lamina, lamina propria, muscularis mucosae Submucosa - loose connective tissue Muscularis externa - two thick layers smooth muscle (circular and longitudinal) Serosa - outer connective tissue layer to connect and suspend tract
52
Types of mucosa
protective absorptive protective and absorptive secretory
53
Name of GI nervous system
enteric
54
name of nerve bundles in GI tract
Ganglia
55
What is the inside of trachea lined with
columnar epithelial cells, grow shorter the further down. contain cilia Goblet cells and sumucosal glands trap foreign particles
56
True/false - bronchioles have hyaline cartilage
false- bronchi and trachea do, but bronchioles have smooth muscle
57
Alveoli
small air sacs formed by squamous simple epithelia, share basal lamina with capillary
58
Structure of liver cells to make liver?
lobules
59
what is the portal triad
a branch of hepatic artery, hepatic portal vein and bile duct
60
function of islets of langerhans
produce hormones such as insulin
61
where are pancreatic digestive juices activated and what is contained
contains, lipases, proteases and nucleases. secreted into duodenum and activated there to prevent digestion of pancreas
62
What is the tunica intima
single layer squamous epithelial cells | seperated from tunica media by internal elastic tissue
63
what is the tunica media
smooth muscle, sometimes elastic fibres
64
what is the tunica adventitia
supporting connective tissue | separated from tunica media by external elastic membrane
65
what is the name of the blood vessels blood supply
vaso vasorum
66
types of capillary
continuous (no gaps) fenestrated (small pores) discontinuous (large cell and basal lamina gaps)
67
veins have
thin t.media and large t.adventitia valves longitudinal smooth muscle
68
true/false- blood flow is regulated to capillaries
true - by precapillary sphincters
69
lymph functions to
immune surveillance at lymph nodes | remove excess fluid from tissues
70
composition of blood
55% plasma and 45% formed elements
71
lifespan of RBC
around 4 months
72
size and function of RBC
7 microns | elastic cytoskelteton to fit through small capillaries and no nucleus to supply greater oxygen to tissues
73
erythrocytes made by
hemopoiesis
74
true/false - platelets have a nucleus
false
75
cell that makes platelets
megakaryocytes
76
Categories of WBC
granulocytes and agranulocytes
77
Neutrophil
multi lobed nucleus | most common leukocyte
78
basophil
rarest leukocyte bilobed nucleus effector cells in allergic reactions, containing granules with pro inflammatory mediators
79
Eosinophil
High eosin affinity bilobed nucleus parasitic infection
80
monocyte
horseshoe nucleus | involved in phagocytosis
81
lymphocytes
non lobed nucleus no visible granules B&T cells acquired immune response