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Flashcards in HIV Deck (44)
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1

HIV seroconversion presents very similarly to what other infection?

Glandular fever

2

How long after the initial infection does HIV seroconversion illness typically occur?

3-12 weeks

3

What is the best test to use for HIV detection at 4 weeks after possible exposure?

p24 antigen test

4

When should initial testing for HIV be done in asymptomatic patients?

4 weeks after potential exposure

5

After an initial negative result when testing an asymptomatic patient for HIV at 4 weeks, when should a repeat test be offered?

12 weeks after potential exposure

6

What is the most common and accurate test for HIV?

HIV antibody test

7

99% of patients with HIV develop antibodies by when?

3 months

8

HAART involves a combination of at least how many drugs from how many different classes?

3 drugs from at least 2 different classes

9

What is the typical combination of drugs used in HAART?

2 NRTIs and 1 of either a NNRTI or protease inhibitor

10

It is recommended that patients with HIV start HAART when?

As soon as the diagnosis is made

11

Zidovudine, abacavir, emtricitabine, tenofovir, zalcitabine, lamivudine and stavudine are all examples of which type of drug?

NRTIs

12

What is a side effect that can be caused by all NRTI drugs?

Peripheral neuropathy

13

What are some side effects of tenofovir?

Renal impairment and osteoporosis

14

Nevirapine and efavirenz are all examples of which type of drug?

NNRTIs

15

Indinavir, nelfinavir, ritonavir and saquinavir are all examples of which type of drug?

Protease inhibitors

16

Raltegravir, elvitegravir and dolutegravir are all examples of which type of drug?

Integrase inhibitors

17

Which group of ART drugs cause side effects such as diabetes, hyperlipidaemia and central obesity?

Protease inhibitors

18

Post-exposure prophylaxis can be used up to how long following exposure to HIV?

72 hours

19

How long should post-exposure prophylaxis be given for?

4 weeks

20

What should be done before starting anyone on HIV post-exposure prophylaxis?

Test for pre-established HIV infection

21

Hairy leukoplakia is an opportunistic infection that can occur in association with a CD4 count of 200-500. What organism is responsible for it?

EBV

22

Kaposi's sarcoma is an opportunistic infection that can occur in association with a CD4 count of 200-500. What organism is responsible for it?

Human herpes virus 8

23

Progressive multifocal encephalopathy is an opportunistic infection that can occur in association with a CD4 count of 100-200. What organism is responsible for it?

JC virus

24

A CD4 count of less than what is an indication to start PCP prophylaxis with low-dose co-trimoxazole?

200

25

Which organism, a cause of meningitis in patients with HIV, stains with India ink?

Cryptococcus

26

Primary CNS lymphoma is an opportunistic infection that can occur in association with a CD4 count of 50-100. What organism is responsible for it?

EBV

27

What is the most common opportunistic infection in AIDS?

Pneumocystis pneumonia

28

What does a CXR of PCP typically show?

Bilateral interstitial pulmonary infiltrates

29

Exercise induced desaturation is a key clinical feature of what opportunistic infection occurring in patients with HIV?

Pneumocystis pneumonia

30

What investigation is often required to demonstrate the pneumocystis organism causing pneumonia?

Bronchoalveolar lavage