Hodgkins Lymphoma

Question 1

Defin

Answer 1

Malof prolif of lymphocytes. Accum= lymphadenop. Can be in periph blood and infilt organs.
In hodgkins mirror image nuclei in reed sternberg cells.
Bimodal yng ad and eld.

Question 2

Cause

Answer 2

Genet
EBV
SLE
Transplant
Obese

Question 3

Px

Answer 3

Large non tender superfic LN- cervical, ax, inguinal.
Fever, wl, night sweat, pruritis, lethargy.
Alc induced node pain
Bronchial or SVC obstruc due to mediastinal LN cause pleural effus.
Cachexia, anaemia, hepatosplenomeg.

Question 4

Investig

Answer 4

Biopsy

Question 5

Ann arbour staging by CXR or CT and biopsy.

Answer 5

1- single LN region
2-2 or more nodal areas same side of diaphragm
3-LN on both sides diaph
4-beyong LN eg liver, BM.

Question 6

Mx

Answer 6

Chemoradiptherapy. With short or long chemo dep on stage.

ABVD- adriamycin, bleomycin, vinblastin, dacarbazine.