Homeostasis W1 Flashcards

1
Q

What is homeostasis?

A

Maintenance of a constant and “normal” internal environment

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2
Q

What is homeostasis like during steady state?

A

Physiological variable is unchanging

Balance between demands placed on body and body’s response to those demands

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3
Q

What causes mean pressure to remain constant even though arterial pressure oscillates over time?

A

Baroreflex responses and kidney function

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4
Q

How does exercise influence metabolism?

A

Increases adipose tissue lipolysis and FFA mobilisation
Increases liver glucose output (glycogenolysis and gluconeogenesis)

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5
Q

How does exercise influence skin?

A

Increases sweat rate

Effects:
Fluid homeostasis
Cardiovascular function
Temperature regulation
Metabolism

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6
Q

How does exercise influence oxygen transport?

A

Increases whole body oxygen uptake
Increases heart rate and cardiac output
Increases ventilation
Increases arterial PO2

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7
Q

How does exercise influence skeletal muscle?

A

Increases ATP turnover
Increases glycogenolysis, Glucose uptake, Lipolysis, FFA uptake
Increases O2 utilisation, CO2 and heat production
Increases blood flow and capillary recruitment

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8
Q

In the biological control system, what are the key components?

A

Control centre
Sensor/receptor
Effector

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9
Q

In the biological control system, what does the control centre do?

A

Assess input and initiates response

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10
Q

In the biological control system, what does the effector do?

A

Changes internal environment back to normal

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11
Q

In the biological control system, what does the sensor/receptor do?

A

Detects changes in the variable

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12
Q

What are biological control systems?

A

Series of interconnected components that maintain physical or chemical parameters at a near constant value

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13
Q

What is negative feedback?

A

Response reverses the initial disturbance in homeostasis

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14
Q

What is positive feedback system?

A

Biological response increases the original stimulus

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15
Q

What is gain (sensitivity of the response)?

A

Degree of which a control system maintains homeostasis

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16
Q

What are examples of homeostatic control?

A

Regulation of body temperature
Regulation of blood glucose
Regulation of cellular homeostasis

17
Q

How does exercise disrupt homeostasis?

A

Changes pH, PCO2 and temperature in cells

18
Q

What is the major test for homeostatic control?

A

Exercise

19
Q

What is adaptation?

A

Change in structure/function

20
Q

What is acclimation?

A

Adaptation to environmental stresses
Improves function of existing system (homeostatic)

21
Q

What is exercise-induced hormesis?

A

A process in which a low-to-moderate dose of potentially harmful stress results in beneficial adaptive response on the cell or organ system

22
Q

What is cell signalling?

A

Communication between cells using chemical messengers
Coordinates cellular activities

23
Q

What are the 5 different cell signalling pathways?

A

Intracrine
Juxtracrine
Autocrine
Paracrine
Endocrine

24
Q

What is intracrine signalling?

A

Cell messengers inside cell triggers response

25
Q

What is juxtracrine signalling?

A

Cell messengers passed between 2 connected cells

26
Q

What is autocrine signalling?

A

Cell messengers acts on that same cell

27
Q

What is paracrine signalling?

A

Cell messengers act on nearby cells

28
Q

What is endocrine signalling?

A

Cell messengers released into blood

29
Q

What is an example of negative feedback?

A

Respiratory system’s control of CO2 concentration in extracellular fluid

30
Q

What is an example of positive feedback?

A

Childbirth