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Bsc Physiology (Year 1) > Hormones In The Digestive System (part 3) > Flashcards

Hormones In The Digestive System (part 3) Flashcards

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1
Q

state the site(s) of production of the hormone - Gastrin

A

G cells in the gastric antrum

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2
Q

state the site(s) of production of the hormone - Ghrelin

A

P/D1 endocrine cells of the oxynit mucosa

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3
Q

state the site(s) of production of the hormone - Leptin

A

chief cells and endocrine P cells

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4
Q

state the site(s) of production of the hormone - Somatostatin

A

enteroendocrine D cells in the antral and fundic mucosa, and along the intestinal mucosa

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5
Q

state the site(s) of production of the hormone - Secretin

A

enteroendocrine S cells of duodenum mucosa

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6
Q

state the site(s) of production of the hormone - Glucose-dependent insulinotropic polypeptide (GIP)

A

enteroendocrine K cells (in the duodenum)

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7
Q

state the site(s) of production of the hormone - Cholecystokinin (CCK)

A

enteroendocrine I cells of the duodenum and jejunum

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8
Q

state the site(s) of production of the hormone - Motilin

A

enteroendocrine M cells (in the duodenum)

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9
Q

state the site(s) of production of the hormone - Pancreatin Peptide YY (PYY)

A

enteroendocrine L cells of the jejunum, ilium and colon

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10
Q

state the site(s) of production of the hormone - Glucagon-Like Peptide 1 (GLP-1)

A

enteroendocrine L cells of the jejunum, ilium and colon

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11
Q

state the site(s) of production of the hormone - Glucagon-Like Peptide 2 (GLP-2)

A

enteroendocrine L cells of the jejunum, ilium and colon

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12
Q

state the site(s) of production of the hormone - Oxynotomodulin (OXM)

A

enteroendocrine L cells of the jejunum, ilium and colon

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13
Q

state the site(s) of production of the hormone - Fibroblast Growth Factor-19 (FGF-19)

A

ilium enterocytes

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14
Q

state the stimulant(s) for secretion for the hormone - Gastrin

A

food ingestion (primarily proteins)

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15
Q

state the stimulant(s) for secretion for the hormone - Ghrelin

A

fasting, before a meal

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16
Q

state the stimulant(s) for secretion for the hormone - Leptin

A
  1. food ingestion
  2. vagal nerve stimulation
  3. Secretin
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17
Q

state the 4 stimulant(s) for secretion for the hormone - Somatostatin

A
  1. intraluminal nutrients and acids
  2. adrenergic stimulation
  3. CCK
  4. Gastrin
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18
Q

state the 2 stimulant(s) for secretion for the hormone - Secretin

A
  1. acidic chyme form stomach

2. digested fats and proteins

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19
Q

state the stimulant(s) for secretion for the hormone - Glucose-Dependent Insulinotropic Polypeptide (GIP)

A

food ingestion (primarily carbs and fats)

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20
Q

state the stimulant(s) for secretion for the hormone - Cholecystokinin (CCK)

A

food ingestion (primarily proteins and fats)

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21
Q

state the stimulant(s) for secretion for the hormone - Motilin

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A

inter-digestive fasting period

22
Q

state the stimulant(s) for secretion for the hormone - Pancreatic Peptide YY (PYY)

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A

food ingestion (primarily fat)

23
Q

state the stimulant(s) for secretion for the hormone - Glucagon-Like Peptide 1 (GLP-1)

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A

food ingestion (primarily carbs and fats)

24
Q

state the stimulant(s) for secretion for the hormone - Glucagon-Like Peptide 2 (GLP-2)

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A

co-secreted with GLP-1 in response to nutrient ingestion

25
state the stimulant(s) for secretion for the hormone - Oxynotomodulin (OXM)
food ingestion (primarily fat)
26
state the stimulant(s) for secretion for the hormone - Fibroblast Growth Factor-19 (FGF-19)
bile acids acting on FXR (a nuclear receptor)
27
state the 2 receptor/site of action for the hormone - Gastrin
1. CCK2 receptor on fundic entero-chromaffin like cells | 2. gastric parietal cells
28
state the receptor/site of action for the hormone - Ghrelin
GH secretagogue receptor 1a
29
state the receptor/site of action for the hormone - Leptin
Leptin receptor OB-R on enterocytes and gastric regal afferent nerves
30
state the receptor/site of action for the hormone - Somatostatin
somatostatin receptor along GI tract and on the pancreas
31
state the receptor/site of action for the hormone - Secretin
secretin receptor on basolateral membranes in the pancreas and kidney
32
state the receptor/site of action for the hormone - Glucose-Dependent Insulinotropic Polypeptide (GIP)
GIP receptor on endocrine pancreas
33
state the 4 receptor/site of action for the hormone - Cholecystokinin (CCK)
1. CCK1 and CCK2 receptors on vagal afferent nerves 2. pancreas 3. gallbladder 4. CNS
34
state the receptor/site of action for the hormone - Motilin
Motilin receptor on muscles of the GI tract
35
state the 3 receptor/site of action for the hormone - Pancreatic Peptide YY (PYY)
1. at least 5 distinct Y receptor sub-types along the pancreas 2. GI tract 3. CNS
36
state the 3 receptor/site of action for the hormone - Glucagon-Like Peptide 1 (GLP-1)
1. GLP-1 receptor along GI tract 2. pancreas 3. CNS
37
state the 3 receptor/site of action for the hormone - Glucagon-Like Peptide 2 (GLP-2)
1. GLP-2 receptors in the GI tract 2. enteric NS 3. CNS
38
state the receptor/site of action for the hormone - Oxynotomodulin (OXM)
GLP-1 and Glucagon receptors
39
state the receptor/site of action for the hormone - Fibroblast Growth Factor-19 (FGF-19)
heteromeric receptor in the liver
40
state the major function(s) of the hormone - Gastrin
1. stimulates gastric acid secretion | 2. stimulates epithelial cell proliferation
41
state the major function(s) of the hormone - Ghrelin
1. affects appetite and feeding 2. stimulates gastric emptying 3. stimulates acid secretion 4. stimulates GH release
42
state the major function(s) of the hormone - Leptin
1. affects appetite and feeding 2. stimulates CCK and GLP-1 secretion 3. modulates intestinal absorption of nutrients
43
state the major function(s) of the hormone - Somatostatin
1. inhibits gastric acid secretion | 2. inhibits endocrine and exocrine pancreatic secretion
44
state the major function(s) of the hormone - Secretin
1. stimulates pancreatic alkaline secretion 2. inhibits gastric mobility and acid secretion 3. plays a key role in osmoregulation
45
state the major function(s) of the hormone - Glucose-Dependent Insulinotropic Polypeptide (GIP)
potentiates glucose stimulated insulin secretion
46
state the major function(s) of the hormone - Cholecystokinin (CCK)
1. reduces feeding/meal size 2. inhibits gastric emptying and acid secretion 3. stimulates gall bladder contraction 4. stimulates pancreatic enzyme secretion
47
state the major function(s) of the hormone - Motilin
induces phase 2 contraction of migrating motor complex (MMC)
48
state the major function(s) of the hormone - Pancreatin Peptide YY (PYY)
1. reduces food intake 2. inhibits gastric emptying 3. inhibits pancreatic secretion
49
state the major function(s) of the hormone - Glucagon-Like Peptide 1 (GLP-1)
1. reduces food intake 2. inhibits gastric emptying and GI secretion 3. inhibits pancreatic secretion
50
state the major function(s) of the hormone - Glucagon Like Peptide 2 (GLP-2)
1. stimulates growth in mucosa 2. inhibits gastric emptying and acid secretion 3. enhances intestinal nutrient absorption and blood flow
51
state the major function(s) of the hormone - Oxynotomodulin (OXM)
1. reduce food intake 2. reduce gastric acid and exocrine pancreatic secretion 3. promotes glucose stimulated insulin secretion
52
state the major function(s) of the hormone - Fibroblast Growth Factor-19 (FGF-19)
1. suppress bile acid secretion 2. stimulate hepatic protein synthesis and glycogenesis 3. suppress gluconeogenesis

Bsc Physiology (Year 1) (34 decks)

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