How Nerves work 2 Flashcards

The Resting Membrane Potential

1
Q

<p>Do hormones or nerves produce faster responses?</p>

A

<p>Nerves</p>

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2
Q

<p>How is the electrical signal of nerves made?</p>

A

<p>Through the three membrane potentials:</p>

<p>Resting membrane potential</p>

<p>Graded membrane potential</p>

<p>Action potential</p>

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3
Q

<p>What is the resting membrane potential responsible for?</p>

A

<p>Keeps cells ready to respond</p>

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4
Q

<p>What is the graded potential responsible for?</p>

A

<p>Determines whether an action potential should be fired</p>

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5
Q

<p>What is the action potential responsible for?</p>

A

<p>Transmits signals over long distances</p>

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6
Q

<p>What is the voltage of the inside of a cell compared to the outside?</p>

A

<p>-70mV</p>

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7
Q

<p>What is responsible for the inside of a cell being -70mV compared to the outside?</p>

A

<p>Leaky K+channels</p>

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8
Q

<p>What is the equilbrium potential?</p>

A

<p>Membrane potential at which the elctrical gradient is exactly equal and opposite to the concentration gradient</p>

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9
Q

The Nernst equation predicts the equilbrium potential, what does this look like?

A
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10
Q

<p>What is 0K inoC?</p>

A

<p>-273oC</p>

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11
Q

<p>What is the equilbrium potential for K+?</p>

A

<p>-90mV</p>

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12
Q

<p>How does the blood brain barrier protect the brain from changes in ion concentration?</p>

A

<p>Cappilaries are especially tight</p>

<p>This is due to astrocytes and tight junctions</p>

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13
Q

<p>What are the typical concentrations of important ions in and outside a cell?</p>

A

<p>K+greater inside</p>

<p>Na+greater outside</p>

<p>Cl-greater outside</p>

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14
Q

<p>What is the equilbrium potential for Na+?</p>

A

<p>+50mV</p>

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15
Q

<p>What is the equilbrium potential for Cl-?</p>

A

<p>-75mV</p>

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16
Q

The goldman equation predicts the equilbrium potential for several ions, what does this look like?

A
17
Q

<p>Why is the normal resting membrane potential (RMP) -70mV?</p>

A

<p>Electrogenic nature of the Na+/K+pump (3 Na+outand 2 K+in)</p>

<p>Lrge intracellular negatively charged molecules</p>

18
Q

<p>What does depolarising mean?</p>

A

<p>Takes the cell towards 0V</p>

19
Q

<p>What does overshoot mean?</p>

A

<p>Polarises in the opposite direction</p>

20
Q

<p>What does repolarise mean?</p>

A

<p>Polarise in original direction</p>

21
Q

<p>What does hyperpolarise mean?</p>

A

<p>Greater polarisation in the same direction</p>