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Flashcards in HTN Deck (45)
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Age can increase your risk for CVD what are these ages?

Male >= 45 yo Women >= 55 yo


Family history can play a part in CVD risk what are these guidelines?

Family history of a premature CVD even (MI, Stent, Angioplasty....) Women


What are some risk factors for CVD?

HTN, Cigarette smoking Dyslipidemia DM CKD Antinflammatory disease


What is the leading cause of death in the US



Primary HTN includes? And this accounts for what percentage of HTN?

  • Idiopathic (Spontaneously)
  • Benign 
  • Essential 


Accounts for 90% of HTNs


Secondary HTN includes?

  • Renal dx 
  • hyperaldosteronism
  • RAS
  • Pheochromocytoma (Adrenal tumors)
  • Preganany - Eclempsia (Seizures that occur during pregnancy) 
  • Thyroid
  • Drugs 
  • Anemia 


What are the classifications of blood pressure?


What the the JNC 8 dosing guidlelines?

  • A) Start one drug, titrate to maximum dose and then add second drug
  • B) Start one drug and then add a second drug before acheiving max dose of initial
  • C) Begin with 2 drugs at the same time, either 2 separate pills or as single combo


What is the first recommendation per JNC 8 for the management of HTN?

for patients >=60

  • In general population >= 60 years 
  • Want to initiate treatment to lower Bp when 
    • SBP >= 150 or DBP >=90 
  • Treatment goal is to lower SBP < 150 and <90 DBP


What is the second recommendation per JNC 8 with patients <60? with DBP

  • Initiate pharmacologic treatment to lower bp at 90 mmHg
  • Goal is to be below DBP 90 
  • Ages 30-59 Grade A
  • 18-39 
  • Grade E, expert opinion 


Recommendation 3 patients <60 JNC 8 


Initiate pharm treament if SBP is >= 140 

Grade E 


Recom 4 JNC 8 >= 18 with CKD

GFR <60 

Lower BP >= 140 or DBP >= 90 

less than those 


JNC 8 18 or older with DM

>= 140/90 


General JNC 8 medication recommendation for nonback population including ones with DM

Initial Treatment?

  • Thiazide diuretics 
  • CCB
  • ACEI 
  • ARBs 
    • Grade B 



Recommendation 7 black population including DM 

Initial treatment 

Thiazide or CCB 

For general black 

Moderate B 

DM grade C 


Recommindation 8-9 

Patients >= 18 with CKD

Patient >= to 18 with CKD

Treatment should include an ACE and an ARB regardless of race or DM status 

If Bp goal is not reached within a month add a second drug from the recommendations from #6 


What were the key messages in JNC 7?

  • For those > 50 SBP is more important than DBP as a CVD risk factor 
  • Starting at 115/75 risk doubles for each increment of 20/10 
  • Those normotensive at age 55 have a 90% lifetime risk of developing HTN 
  • Certain high risk conditions are compeling indications for certain drug classes 
  • Most patients require 2 or more antihypertensive med to achieve goal 


Post MI patients initial therapy options?

  • BB, ACEI, Aldosterone antagonists 


Patients with high CAD risk shoudl use?

BB and CCBs mostly 


Patients with DM should use what meds?

ACE and ARBs


Patients with CKD should use?



What is the best choice for blacks? And what is the combination used that gives there treatment a similar effect as the nonblack populations?

Diuretics and CCBs

Thiazide + ACE is best 


What should pregnant patients use? 

What should be avoided?

Methyldopa, hydralazine, BBs

Avoid ACEI, ARBs, Renin-I


In elderly you would treat them the same as you would any patient but you should avoid?


Vasodilators, central a2 agonists, and a-blockers 


ACEIs should be avoided in patients with? 

History of angioedema 


Chlorthalidone is more effective than ____ and it is a?

HCTZ and is a thiazide diuretic 

Not used in patients with renal insufficiency 


Thiazides are best for what population? 

These are synergisitic with?

Can cause?

Black population 

Synergistic with ACE and BBs

Hypokalemia, Hyperlipidemia, Hyperglycemia, Hyperuricemia


Diuretics increase? what cholesterol?

LDL and TGs 


Potassium ___ diuretics are often used in combination with wht?

Caution should be used in patients with what insufficiency?

Caution when using with?


Renal insufficiency 

Caution with ACEI, ARBs and Renin-I


Loop diuretics are reserved for patients with?

Renal insufficiency