Hyperlipidaemia and severe hypertriglyceridaemia in pregnancy

Question 1

In pregnancy how much do lipid levels and triglyceride levels increase?

Answer 1

1) Lipids - 30-50%
2) TGs 2 - 4 X

Question 2

After delivery how long does it take for cholesterol level to return to pre-pregnancy values?

Answer 2

72 hours

Question 3

During pregnancy total cholesterol nor TF should exceed what level?

Answer 3

2.8 mol/L

Question 4

What pregnancy complicationsa are associated with TG >2.8

Answer 4

PIH
PET
GDM
LHA
Acute pancreatitis

Question 5

Graph explained levels of lipid values in pregnancy

Answer 5

Question 6

What is considered severe gestational hypertriglycerideamia?

Answer 6

TG > 95th or >11.4
Occurs in 3rd trimester
Considered life threatening condition
Commonly associated with Familial conditions

Question 7

What is the inheritance of familial hypercholesterolaemia?

Answer 7

AD
LDL receptor deficiency

• patient with this condition will experience maternalsupraphysiological hypercholesterolaemia - associated with endothelial damage and PET

Question 8

Hypertriglyceridaemia-induced acute pancreatitis accounts for what proportion of pancreatitis in pregnancy?

Answer 8

58%

3rd comments cause (this doesn’t make sense but what it says in article)

Question 9

Which patients should have triglyceraides measured in pregnancy?

Answer 9

Question 9

Table explaining management options

Answer 9

Question 10

Fat in diet related to severity of hypertriglyceridaemia

Answer 10

Mild-mod: 30%
Mod-serve: 20%, no improvement 5-10% calorie input

Question 11

A does of 2-4% omega 3 can lower TG by how much?

Answer 11

40%

Question 12

What are the only lipid lowering medication approved in pregnancy?

Answer 12

Bile acid sequestants
Can reduced LDL by 20-30% bur increase VLDL & TG
Do not give with hypertriglyceridemia

Question 13

When to stop statins pre pregnancy

Answer 13

1-2 months