Hypersensitivity Flashcards
(86 cards)
1
Q
allergies
A
type 1
2
Q
atopy
A
type 1
3
Q
passive cutaneous anaphylaxis
A
type 1
4
Q
hay fever (Seasonal allergic rhinitis)
A
type 1
5
Q
allergic asthma
A
type 1
6
Q
hives (urticaria)
A
type 1
7
Q
latex sensitivity
A
type 1
type 4
8
Q
wheal and flare rxn
A
type 1
9
Q
eczema
A
type 1
10
Q
dermatitis or local skin inflammation
A
type 1
11
Q
drug anaphylaxis
A
type 1
12
Q
rhinitis
A
type 1
13
Q
angioedema
A
type 1
14
Q
penicillin-induced rxn
A
type 1
15
Q
food allergies
A
type 1
16
Q
reaction to bee venom/sting
A
type 1
17
Q
atopic dermatitis
A
type 1
18
Q
transfusion rxn
A
type 2
19
Q
drug induced AIHA
idiopathic AIHA
WAIHA
A
type 2
20
Q
HDN
A
type 2
21
Q
hyperacute graft rejection
A
type 2
22
Q
goodpasture syndrome
A
type 2
23
Q
Myasthenia gravis
A
type 2
24
Q
Graves dse
A
type 2
25
type 2 DM (insulin independent)
type 2
26
ADCC
type 2
27
classical pathway of complement activation
type 2
28
cell surface coating by Ab
type 2
29
kernicterus (>20 mg/dL bilirubin)
type 2
30
erythroblastosis fetalis (severe HDN)
type 2
31
PCH
type 2
32
cold agglutinins
type 2
33
acrocyanosis
type 2
34
CCAD/CHD
type 2
35
Hashimoto’s
type 2 (pwede rin ata type 4???)
36
SLE
type 3
37
RA
type 3
38
post strep glomerulonephritis
type 3
39
vasculitis
type 3
40
serum sickness
type 3
generalized
41
arthus rxn
type 3
localized
42
LE
type 3
43
drug rxn
type 1 (penicillin)
type 2
type 3
44
granulomas
type 4
45
M. tuberculosis (TB)
type 4
46
M. leprae (Leprosy)
type 4
47
P. carinii
type 4
48
Leishmania spp
type 4
49
HSV
type 4
50
poison oak/ivy
type 4
51
nickel salts (metal)
type 4
52
hair dye/cosmetic components
type 4
53
contact dermatitis
type 4
54
hypersensitivity pneumonitis
type 4
55
tuberculin
type 4
56
farmer’s lung
bird breeder’s lung dse
humidifier/AC lung dse
type 4
57
type 1 DM
type 2
58
acute/chronic graft rejection
type 4
59
IMMUNE MEDIATOR: TYPE 1
IgE
60
IMMUNE MEDIATOR: TYPE 2
IgG or IgM
61
IMMUNE MEDIATOR: TYPE 3
IgG or IgM
62
IMMUNE MEDIATOR: TYPE 4
T cells
63
SYNONYM: TYPE 1
Anaphylactic
64
SYNONYM: TYPE 2
Ab-mediated cytotoxic
65
SYNONYM: TYPE 3
Immune Complex-mediated
66
SYNONYM: TYPE 4
Cell-mediated or Delayed
67
TIMING: Type 1, 2, 3
Immediate
68
TIMING: Type 4
delayed
69
1. mediated by antibodies
2. mediated by sensitized T cells
1. immediate hypersensitivity
2. delayed
70
ANTIGEN: Type 1
heterologous
71
ANTIGEN: Type 2
cell surface
autologous
heterologous
72
ANTIGEN: Type 3
soluble
autologous
heterologous
73
ANTIGEN: Type 4
autologous
heterologous
74
complement involvement: Type 1
NO
75
complement involvement: Type 2
YES
76
complement involvement: Type 3
YES
77
complement involvement: Type 4
NO
78
IMMUNE MECHANISM:
Mediator release from IgE-sensitized mast cells and basophils
type 1
79
IMMUNE MECHANISM:
Cell destruction due to Ab and complement, opsonization, or ADCC
Cell function INHIBITED by Ab binding
Cell function STIMULATED by Ab binding
type 2
80
IMMUNE MECHANISM:
Ag-Ab complex activates complement proteins
Neutrophils are recruited and release lysosomal enzymes that cause tissue damage
type 3
81
IMMUNE MECHANISM:
Ag-sensitized Th1 cells release cytokines that recruit macrophage and induce inflammation or activate cytotoxic T cells to cause direct cell damage.
Type 4
82
Ab in type 4
NONE (difference from the 3 types)
83
EFFECTOR CELLS: Type 1
Basophil
Mast cells
84
EFFECTOR CELLS: Type 2
PMN
NK
MICROORG
85
EFFECTOR CELLS: Type 3
PMN
MICROORG
86
EFFECTOR CELLS: Type 4
T cells
