Flashcards in Immune Response & Inflammation (Part 1)- Exam 3 Deck (216)
What is the immune system?
System that protects individual against invasion by microorganisms
What is important about immunity in regards to normal body tissue?
Must recognize and destroy invaders, BUT do no damage to normal body tissue
How does the immune system destroy invaders?
Destruction by phagocytosis and/or membrane lysis
Where does destruction of the foreign invader occur?
Takes place at the point of infection; must have ability to activate and move all components to the site
How does the immune system move all components to the site of infection?
Vascular system, lymphatic system, interstitial fluid
Who are the major players in the immune response?
WBCs, Antibody, Complement System (variety of chemical mediators)
Anything foreign that enters the body; can bind to antibody and/or can bind to receptors on the T or B cells
antigenic cells that will be destroyed by immune system
any substance that can stimulate an immune response; all are antigenic (can bind with antibody); not all antigens are immunogens
Are all immunogens antigenic (can bind with antibody)?
Are all antigens also immunogens?
antigen with ability to cause disease; usually microorganism or toxin
What are 4 different types of antigens?
What are some examples of microorganism antigens?
Bacteria, viruses, parasites, fungi, yeasts
What are allogenic cells?
Cells from genetically dissimilar individual
Describe infected cells.
Cells inhabited by viruses, certain bacteria, parasites
How many circulating WBCs does the average adult have?
What is the normal WBC count?
5,000 - 10,000 per mL
What percent of total leukocytes are neutrophils?
40-75% of total
What are the first leukocytes to destroy invaders?
What percent of total WBC count are lymphocytes?
20-45 % of total
What are two examples of lymphocytes?
T cells/ B cells
What percent of total WBC count are monocytes?
Up to 8%
What percent of total WBC count are eosinophils?
1 - 6 %
What percent of total WBC count are basophils?
Up to 1%
What types of leukocytes are most numbers? What are they named after?
Granulocytes; names for granules in the cytoplasm
What are three examples of granulocytes?
What do monocytes become in the body tissues?
What are large white cells?