Immune Response & Inflammation (Part 1)- Exam 3 Flashcards Preview

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Flashcards in Immune Response & Inflammation (Part 1)- Exam 3 Deck (216)
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1

What is the immune system?

System that protects individual against invasion by microorganisms

2

What is important about immunity in regards to normal body tissue?

Must recognize and destroy invaders, BUT do no damage to normal body tissue

3

How does the immune system destroy invaders?

Destruction by phagocytosis and/or membrane lysis

4

Where does destruction of the foreign invader occur?

Takes place at the point of infection; must have ability to activate and move all components to the site

5

How does the immune system move all components to the site of infection?

Vascular system, lymphatic system, interstitial fluid

6

Who are the major players in the immune response?

WBCs, Antibody, Complement System (variety of chemical mediators)

7

Antigen

Anything foreign that enters the body; can bind to antibody and/or can bind to receptors on the T or B cells

8

Target Cells

antigenic cells that will be destroyed by immune system

9

Immunogen

any substance that can stimulate an immune response; all are antigenic (can bind with antibody); not all antigens are immunogens

10

Are all immunogens antigenic (can bind with antibody)?

Yes

11

Are all antigens also immunogens?

No

12

Pathogen

antigen with ability to cause disease; usually microorganism or toxin

13

What are 4 different types of antigens?

Microorganisms
Allogenic cells
Malignant cells
Infected cells

14

What are some examples of microorganism antigens?

Bacteria, viruses, parasites, fungi, yeasts

15

What are allogenic cells?

Cells from genetically dissimilar individual

16

Describe infected cells.

Cells inhabited by viruses, certain bacteria, parasites

17

How many circulating WBCs does the average adult have?

75 billion

18

What is the normal WBC count?

5,000 - 10,000 per mL

19

What percent of total leukocytes are neutrophils?

40-75% of total

20

What are the first leukocytes to destroy invaders?

Neutrophils

21

What percent of total WBC count are lymphocytes?

20-45 % of total

22

What are two examples of lymphocytes?

T cells/ B cells

23

What percent of total WBC count are monocytes?

Up to 8%

24

What percent of total WBC count are eosinophils?

1 - 6 %

25

What percent of total WBC count are basophils?

Up to 1%

26

What types of leukocytes are most numbers? What are they named after?

Granulocytes; names for granules in the cytoplasm

27

What are three examples of granulocytes?

Neutrophils
Basophils
Eosinophils

28

What do monocytes become in the body tissues?

Macrophages

29

What are large white cells?

Monocytes

30

What do lymphocytes differentiate into?

B and T Cells