Immune Tissue Hypersensitivity Flashcards Preview

Immunology, Rheumatology, Dermatology > Immune Tissue Hypersensitivity > Flashcards

Flashcards in Immune Tissue Hypersensitivity Deck (13)
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1

What type of antigen does type 4 HS recognize?

Soluble and Insoluble

2

What effector antibody does type 3 HS use?

IgG

3

Four downstream type 1 HS manifestations

1. Wheal and Flare
2. Acute Rhinitis
3. Anaphylaxis
4. Mast Cell activation

4

Four downstream Type 4 HS manifestations

1. Induration/ Tuberculin Rxn via Th1/Macro
2. Contact Dermatitis (shit haptens)
3. Chronic Asthma//Rhinitis
4. Graft Rejection

5

What effector antibody does type 2 HS use?

IgG

6

What effectors does type 4 use?

T-helpers and CTLs

7

What type of antigen does type 2 HS recognize?

Non-souble; Either Cell-Antigen or Cell-Receptor complexes

8

Four downstream type 3 HS manifestations

1. Arthus Reaction
2. Serum Sickness
3. Complex build up in joints/capillary beds
4. Activate complement and phagos via Fc

9

Four downstream type 2 HS manifestations

1. Drug Allergies
2. Chronic Urticartia
3. RBC ABO rejection
4. Complement/NK/Phago activation

10

What type of antigen does type 3 HS recognize?

Soluble

11

What type of Antigen does type 1 HS recognize?

Soluble

12

What are the four types of G&C Tissue Hypersensitivities?

1. IgE Immediate Hypersensitivity
.2. IgG Non-soluble/Cell-Surface Mediated
3. IgG Soluble Complex Remover
4. T-cell Delayed Hypersensitivity

13

What effector antibody does type 1 HS use?

IgE