Immunity: Complement Flashcards
1
Q
Major component in complement activation
A
C3b
2
Q
C3 convertase in the classical/lectin pathway
A
C4bC2a
3
Q
What is C3 convertase in the alternative pathway?
A
C3bH2OBb
4
Q
What is C5 convertase in the classical/lectin pathway?
A
C4bC2aC3b
5
Q
What is C5 convertase in the alternative pathway?
A
(C3b)2BbP
6
Q
What is the first member of the membrane attack complex
A
C5b
7
Q
When does the MAC change shape and “become a drill”
A
C8 & C9 attach
