Immunology: Immunoglobulins

Question 1

Crosses placenta

Answer 1

IgG

Question 2

Found one the serum and body secretory

Answer 2

IgA

Question 3

Pentameric structure with J chain

Answer 3

IgM

Question 4

Fc of this Ig binds to receptors on the mast cells and basophils

Answer 4

IgE

Question 5

Trace amounts in blood

Answer 5

IgD

Question 6

Half-life of 26 days

Answer 6

IgG

Question 7

First Ig to appear on lymphocyte membrane

Answer 7

IgM

Question 8

Largest total in body

Answer 8

IgA

Question 9

Involved in immediate hypersensitivity reactions

Answer 9

IgE

Question 10

Occurs in large amounts on B lymphocyte plasma membrane

Answer 10

IgD

Question 11

Involved in immunity to parasites

Answer 11

IgE

Question 12

Predominant in the early primary response to most antigens

Answer 12

IgM

Question 13

Major opsonization antibody

Answer 13

IgG

Question 14

Predominant Ig produced in fetus

Answer 14

IgM

Question 15

Most exist as monomers but some as dimers or trimers

Answer 15

IgA

Question 16

Made of 2 heavy and light chains, forming a monomer

Answer 16

IgE

Question 17

Trace amounts of blood, lowest level of the Ig’s

Answer 17

IgE

Question 18

May have some antibody activity due to a limited number of antigens

Answer 18

IgD

Question 19

Produced by B lymphocytes and plasma cells that are located primarily in the spleen, tonsils, adenoids, and lining the respiratory and digestive tracts

Answer 19

IgE

Question 20

Can be inactivated by protease produced by various bacteria

Answer 20

IgA

Question 21

Elevated in cord blood may be indication of an infection at birth

Answer 21

IgM

Question 22

Activates complement via classical pathway

Answer 22

IgG

Question 23

Primary Ig made to carbohydrate antigens

Answer 23

IgM

Question 24

Consists of 2 monomers and J chain and secretory component

Answer 24

IgA

Question 25

Most active in complement activation

Answer 25

IgM