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Flashcards in Immuno 2 Deck (32):
1

lymph vessel muscular movements are to

help move lymph through vessel and return lymph back to blood venous system

2

2/3 of lymph returns to the venous system via

a duct in the Left upper chest (thorax)

3

1/3 of the lymph returns to the venous system via

a duct in the Right upper chest (thorax)

4

are lymph nodes an organ?

yes, they are encapsulated with specific parts

5

first lymph node on a route encounters

-pathogen (invaders) themselves
-B and T lymphocytes
(invaders and key players of immune system connecting here)

6

what is the eye disease EKC?

epidermic keratoconjunctivitis
(affects conjunctiva and cornea)

7

how do pre auricular nodes relate to diagnosis of EKC?

palpating the pre auricular nodes (in front of the ears) may be swollen or sore
(the drainage of the eye goes to this lymph node first)

8

what are the two conditions of viral infection

-virus is in interstitial fluid, floating around, and an easy target
-virus is in cell and using host cell machinery

9

viral infection inside the cell has a _____ response activated

cellular

10

examples of cellular response with virus inside cell

-tumor (changed cell with antigen presenting)
-transplant rejection (foreign cells in body)

11

bacterial or viral infection outside of cell has _____ response activated

humoral

12

immune cell, lymphocyte, involved with cellular response

T lymphocyte

13

immune cell, lymphocyte, involved with humoral response

B lymphocyte

14

when is it determined that a lymphocyte will become a B or T cell?

predetermined during embryonic development, certain number of each one is pre-programmed

15

precursor cells for B/T lymphocytes are ____ cells found where?

stem cells found in the blood forming stem cells in the embryo

16

organ involved in processing during embryonic development for B cells

bursal equivalent cells
(named after Bursa of Fabricius in chicken)

17

organ involved in processing during embryonic development of T cells

thymus (larger as a child, and disappears as an adult)
-thymus is found in chest behind sternum in midline

18

for B lymphocytes, where do cells migrate to from the bursal equivalent cells

they migrate to peripheral sites in lymph nodes

19

where do B cells migrate to in the lymph node

cortical follicles
(outside cortex)

20

gearing up of the immune system to produce the B cells is called

clonal selection

21

how is clonal selection triggered?

BCR (B cell receptor) test batch of antibodies on the surface are looking for antigens they can hook up to
-if B cell comes upon antigen and binds to it, you start process that triggers B cells

22

what occurs in clonal selection when B cells are triggered and how many antibodies /week could they make ?

B cells that are triggered double in size and start dividing (proliferation)
could produce 20,000 B cells/ week

23

the activated B cells that are proliferated and activated are now called

plasma cells

24

where do plasma cells go and how fast can they make antibodies ?

they go to the site of infection and produce about 2,000 antibodies/ second there

25

how long is the plasma cell lifespan

they don't divide and last for about a week

26

processed T cell is called a

competent cell (ready to be part of immune system)

27

where do competent T cells migrate to in the lymph nodes

paracortical area (just inside cortex) of lymph nodes

28

list 3 types of T cells based on function

1. killer
2. helper
3. regulatory

29

killer T cells

cytotoxic lymphocytes (CDL)
-encounter cells with virus in it, and respond by destroying that cell

30

helper T cells

(TH) "quarterback" cell of adaptive system that secretes cytokines that help coordinate the response

31

regulatory T cells

not much know, but thought that it regulates there response

32

2 types of T cells based on biochemical markers

-T4 (CTLs)
-T8 (TH)