Immuno - Abs Flashcards

1
Q

Dermatomyositis

A

Anti-Jo1

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2
Q

*Sjogren (dry eyes and parotid swelling)

A

Anti-Ro and anti-La

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3
Q

*CREST (Limited cutaneous scleroderma)

?tight lips lol

A

Anti-centromere

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4
Q

Diffuse scleroderma

A

Anti-topoisomerase/SCL70

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5
Q

Primary biliary cholangitis

A

Anti-mitochondrial

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6
Q

*Myasthenia gravis (weakness + ptosis/droopy lid)

A

Anti-Acetyl choline receptor

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7
Q

*Rheumatoid arthritis (Aches all over + joint stiffness +joint swelling + XR shows erosive joint changes)

A

Anti cyclic citrullinated peptide, rheumatoid factor

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8
Q

*Systemic Lupus Erythematosus

young person + pleuritic chest pain, joint pain

A

Anti nuclear antibodies (Smith, Ro, La, histones) and anti-double strand DNA antibodies // C3 and C4

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9
Q

*Wegener’s (Granulomatous polyangitis)

Involves upper and lower airways + kidneys

A

C-ANCA (Anti-PR3*) - cytoplasmic antineutrophil cytopalsmic antibodies

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10
Q

Churg-Strauss (eosinophilic granulomatous polyangitis)

A

P-ANCA (Anti-MPO) - perinuclear antineutrophil cytoplasmic antibodies

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11
Q

Microscopic polyangitis

A

P-ANCA (Anti-MPO) - perinuclear antineutrophil cytoplasmic antibodies

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12
Q

Primary sclerosing cholangitis

A

P-ANCA (Anti-MPO) - perinuclear antineutrophil cytoplasmic antibodies

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13
Q

Autoimmune hepatitis

A

Anti-smooth muscle, anti liver-kidney microsomal-1

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14
Q

Autoimmune pancreatitis

A

IgG4

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15
Q

Goodpasture’s disease

A

Anti-glomerular basement membrane (Type IV collagen)

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16
Q

Coeliac

A

Anti-tissue transglutaminase (Anti TtG antibody), anti-endomysial, anti- gliadin

17
Q

T1DM

A

Anti pancreatic beta cell, anti-glutamic acid decarboxylase

18
Q

Antiphospholipid syndrome

A

Anti-cardiolipin, lupus anticoagulant

19
Q

Graves

A

Anti-TSH receptor

20
Q

*Hashimoto’s

A

Anti-thyroperoxidase, anti-thyroglobulin

21
Q

Pernicious anaemia

A

Anti-parietal cell, anti- intrinsic factor

22
Q

Multiple sclerosis (muscle fatigue and double vision)

A

Anti-myelin basic protein, anti-proteolipid

23
Q

Membranous glomerulonephritis

A

Anti phospholipase A2 receptor

24
Q

Polymyositis

A

Anti-Jo1

25
Q

Mixed connective tissue disease

A

Anti-U1RNP

26
Q

Dermatitis herpetiformis

A

Anti-endomysial antibody

27
Q

Autoimmune thrombocytopenic purpura

A

Anti-glycoprotein IIb-IIIa

28
Q

Autoimmune haemolytic anaemia

A

Anti Rh blood group antigen