Immunohistochemistry Flashcards
Location (63 cards)
1
Q
Clusters of Differentiation (CD)
A
Membranous
2
Q
HER2/neu
A
Membranous
3
Q
EGFR
A
Membranous
4
Q
E-cadherin
A
Membranous
5
Q
TTF-1
A
Nuclear
6
Q
CDX2
A
Nuclear
7
Q
Myogenin
A
Nuclear
8
Q
WT1
A
Nuclear
9
Q
p53
A
Nuclear
10
Q
p63
A
Nuclear
11
Q
Esterogen Receptor (ER)
A
Nuclear
12
Q
Progesterone Receptor (PR)
A
Nuclear
13
Q
Ki-67 / MIB1
A
Nuclear
14
Q
Cytokeratins (CK)
A
Cytoplasmic
15
Q
Desmin
A
Cytoplasmic
16
Q
Vimentin
A
Cytoplasmic
17
Q
Actin
A
Cytoplasmic
18
Q
ACTH
A
Cytoplasmic
19
Q
S100
A
Nuclear and Cytoplasmic
20
Q
p16
A
Nuclear and Cytoplasmic
21
Q
Calretinin
A
Nuclear and Cytoplasmic
22
Q
AMACR / Racemase
A
Cytoplasmic granular (mitochondrial / peroxisomal)
23
Q
Napsin A
A
Cytoplasmic granular (lysosomal)
24
Q
HepPar1
A
Cytoplasmic granular (mitochondrial)
25
CD30 in classical Hodgkin Lymphoma
Cytoplasmic dot-like (golgi staining)
26
CD15 in classical Hodgkin Lymphoma
Cytoplasmic dot-like (golgi staining)
27
Cytokeratins (CKs) in Neuroendocrine carcinomas
Cytoplasmic dot-like (perinuclear)
| Punctate
28
PAX8
Nuclear
29
p40
Nuclear
30
Ki-67 / MIB1 in Hyalinizing trabecular tumor/adenoma of thyroid
Membranous / Cytoplasmic
31
GFAP
Cytoplasmic
32
Neurofilament
Cytoplasmic
33
HMB45
Cytoplasmic
34
Melan-A
Cytoplasmic
35
Trypsin
Cytoplasmic
36
Beta-catenin (normal)
Membranous in Epithelial cells
| Cytoplasmic in Stromal cells
37
Beta-catenin in Desmoid-type Fibromatosis and some Colon CAs
Nuclear
38
CD30 in Anaplastic Large cell Lymphoma
Cytoplasmic dot-like (golgi staining)
39
CK20 in Merkel cell CA
Perinuclear dot-like (punctate)
40
ATRX
Nuclear
41
BCL2
Membranous and Cytoplasmic
42
POSITIVE or NEGATIVE
BCL2 in Follicular lymphoma
Positive
43
BCL2 in reactive follicles
Negative
44
BCL10
Cytoplasmic
45
Ber-EP4
Membranous
46
Brachyury
Nuclear
47
CA 19-9
Cytoplasmic
48
h-Caldesmon
Cytoplasmic
49
h-Caldesmon in Leiomyosarcoma
Positive
50
POSITIVE or NEGATIVE
h-Caldesmon in myofibroblastic lesions such as fibromatosis
Negative
51
CD1a
Membranous
52
CD31
Membranous and Cytoplasmic
53
CD34
Membranous and Cytoplasmic
54
CD34 in DFSP vs. Dermatofibroma
- DFSP+
| - Dermatofibroma-
55
CD56 / NCAM
Membranous
56
CD68
Membranous and Cytoplasmic
57
CD99 / MIC2 / O13
Membranous and Cytoplasmic
58
CD138
Membranous
59
CDK4
Nuclear
60
CEA
Cytoplasmic
61
Chromogranin A
Cytoplasmic (granular)
62
c-Kit / CD117
Membranous and Cytoplasmic
63
c-Kit/CD117 in Thymoma vs Thymic CA
- Thymoma-
| - Thymic CA+
