Immunologic memory and vaccine Flashcards

1
Q

Risks with Passive immunotherapy

A
  • IgE production causing systemic anaphylaxis
  • IgG or IgM anti-isotype AB causing complent-activating immune complexes leading to Type 3 HS
  • Anti-allotype AB
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2
Q

DTaP

A

D: C. diphtheriae Toxoid

T: C. tetani Toxoid

aP: B. pertussis Toxoid + filamentous hemagglutinin

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3
Q

Mrr. V.Z. MAPSY

A

Live Viral Vaccines

  1. Mumps
  2. Rotavirus
  3. Rubella
  4. Varicella - Zoster
  5. Measles
  6. Adenovirus
  7. Polio (Sabin)
  8. Small Pox
  9. Yellow Fever
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4
Q

Example of Natural Passive immunity

A
  • Placental IgG transport
  • Colostrum
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5
Q

Example of Artificial Passive immunity

A
  • Spider/snake bite
  • Antitoxin against botulism, Diphtheria
  • Pooled hman Ig versus hepatitis A and B, Measles, Rabies, VZV or Tetanus
  • Humanized monoclonal AB versus RSV
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6
Q

Hib vaccine

A
  • H. influenzai
  • Capsular polysaccharide and protein
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7
Q

RIP - A

(Rest In Peace Always)

A

Killed viral vaccines

Rabies

Influenza

Polio (Salk)

A Hepatitis

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8
Q

MCV-4 vaccine

A

N. meningitidis

4 capsular serotypes (Y, W-135, C, A) and protein

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9
Q

Example of Natural Active immunity

A

Recovery from infection

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10
Q

PCV vaccine

A

S. pneumoniae in pediatrics

13 Capsular serotypes and proteins

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11
Q

Examples of Artificial Active immunity

A
  1. Hep B component vaccine
  2. Diphtheria, Tetanus, Pertussis Toxoid vaccine
  3. Haemophilus capsular vaccine
  4. Polio live or inactivated vaccine
  5. Measles, mumps, rubella attenuated vaccine
  6. Varicella attenuated vaccine
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12
Q

PPV vaccine

A

S. pneumoniae Adults

23 Capsular serotypes

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