Immunology Flashcards
Describe the main role of the immune system
Combat opportunistic infections in the body
What is innate immunity
The bodies physical barriers, phagocytosis
Describe physical barriers
Skin, muscular membranes, sweat, tears
What are the main cells in the innate immune system
Phagocytes, neutrophils, macrophages, monocytes
Explain phagocytosis
Movement towards, adhesion, fusion, creation of capsular (phagosome), fusion of lysosome with phagosome, digestive enzyme
What is a neutrophil
White blood cell, engulfing/ destruction
What is a macrophage
Antigen presenting cell- produces antibodies, involved in engulfing and digestion
What is a monocyte
Largest WBC, engulf more, differentiate into macrophages, found in the bone marrow
What is self tolerance
When your immune cells and immune cells exist together in unison/ don’t attach
What are eosinophils/ mast cells
Combat infections, involved in allergy/ asthma, release histamine
What is a basophil
Involved in parasitic infections, have large cytoplasmic granulates with inflammatory mediators
What is a natural killer cell
White blood cells that destroy infected and diseased cells, communicate with interferon gamma, self proliferate
What are dendritic cells
Regulate the adaptive immune response, antigen- presenting cells-capture and present antigen to lymphocytes
What are primary and secondary lymphoid cells
Primary- thymus, bone marrow (b+ T cell formation/ maturation)
Secondary- lymph nodes, tonsils, spleen (adaptive immunity)
+ lymph vessels
Explain lymphatic system
Drainage of tissue
Absorption & transport of fatty acids & fats
Immunity
