Infectious Disease (guest lecturer)TEST 3 Flashcards Preview

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Flashcards in Infectious Disease (guest lecturer)TEST 3 Deck (26):
1

Epidemiology

study of distribution of determinants in population and application of these determinants to control health

2

In Sub Saharan Africa, what are the leading causes of death?

AIDS and Tuberculosis

3

Is HIV a disease or a pathogen?

Pathogen

4

AIDS?

Disease

5

Ro

The basic reproductive number: Average number of people an infected person can infect before they recover or die

6

Pathogen

org. that causes disease

7

Infection

replication of pathogens inside org

8

Disease

Change from normal phsyio to bad

9

If R0 is less than 1 what happens to the disease?

It dies out

10

If Ro is more than 1 what happens to disease

It persists

11

Equation for Ro?

infectious contact rateXduration of infection

12

Ro of sneezing on someone=

probability being sneezed on will lead to infectionXdays you are sneezing

13

What is the main thing to consider when looking at Ro?

The generation time of the infection!(time between getting infection and being able to infect someone else)

14

Reff

Reproductive number (consiers amount of people actually suseptible to the infection

15

If R0=4 how many people do we need vacinnated to stop the disease?

75% because of herd immunity (because we need 3/4 of infections to fail to get Ro=1)

16

If Ro=4 but Reff=2 how many people need to be vaccinated?

Only 50% because only half the population can get the disease (Reff) so that makes R0 basically 2 meaning we need 50% of the people who can get infections to be immunized to get R0=1

17

Latency Period

Time you have been infected but can not infect other people (this is super long time for HIV)

18

When infection preceeds disease what happens?

You can infect other people but you don't even know you are sick because you don't have symptons yet(AIDS)

19

SIR Model

a simple view of the world in terms of infectious disease:
Suseptibility (transmission) Infectious (recovery) Recovered

20

What effects Transmission Rate?

dependent on how many infected people are around you

21

B=

infectious contact rate

22

Transmision Viurlence Tradeoff

Good pathogens are good at spreading disease so they don't want to killl the host

23

Vector

something that spreads a pathogen (like a mosquito)

24

Why does mosquito control work?

Because it shortens the days that mosquitos are alive an infectious and also shortens the number of days that they are infectious

25

Zoonotic Pathogens

Pathogens that come from animals

26

How did we discover origin of HIV?

By looking at the place with the most amount of HIV strains (the place with most diversity)