Inflammation Flashcards
A protective universal response to tissue damage
Inflammation
Beneficial inflammation is usually for an _______ type of inflammation
Acute
Harmful inflammation is usually for an ______ type of inflammation
Chronic
Beneficial Function of Inflammation
- Contain damage and Isolate injury
- Destroy cause of injury
- Destroy resulting nectrotic cells and tissues
- Prepare tissue for healing and repair
Harmful effects of Inflammation
- Digestion of normal tissues
- Swelling
- Inappropriate inflammatory response
The original 4 Cardinal signs of inflammation
- Rubor
- Calor
- Tumor
- Dolor
5th Cardinal sign of inflammation by Virchow
Functio Laesa
Cardinal sign that causes redness
Rubor
Cardinal sign that causes heat
Calor
Cardinal sign that causes swelling
Tumor
Cardinal sign that causes pain
Dolor
Cardinal sign that causes loss of function
Functio Laesa
Chronic cardinal signs
- Rubor
- Calor
- Tumor
- Dolor
- Functio Laesa
Acute cardinal signs
- Rubor
- Calor
- Tumor
- Dolor
Components of Inflammation:
Initial Response of the immune system
Vasoconstriction
Components of Inflammation:
Increased diameter of blood vessels
Vasodilation
Components of Inflammation:
Increased vascular permeability
Endothelial Activation
Components of Inflammation:
- WBCs enter site of injury and kill organisms and remove debris
Neutrophil Activation
Neutrophil Activation releases what
Chemokines
Sequential Steps of a typical Inflammatory Reaction
- Recognition of Stimulus
- Recruitment of WBCs and proteins to site
- Removal of stimulus
- Regulation of response
- Repair
Short type of inflammation
Acute
Responsible WBCs for Acute inflammation
Neutrophils
Long term type of inflammation
Chronic
Responsible WBCs for Chronic inflammation
Monocytes