Flashcards in Influence of renal insufficiency on drug elimination and response Deck (4)
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1
Q
What are pharmacokinetics?
A
How the body handles drugs
2
Q
What are pharmacodynamics?
A
How tissue responds to drugs
3
Q
What are the criterion used for impaired renal function?
A
Narrow range drugs
Drugs that are dependent on renal elimination
4
Q
What are narrow range, renally eliminated drugs?
A
Digoxin (patients with renal dysfunction
Lithium (used in bipolar disorder and lots of attention to renal function must be paid)
Hypoglycaemics (insulin is substantially removed by kidneys in a complex manner)
Methotrexate (an anticancer drug)
Aminoglycoside antibiotics
