Flashcards in Influence of renal insufficiency on drug elimination and response Deck (4)
What are pharmacokinetics?
How the body handles drugs
What are pharmacodynamics?
How tissue responds to drugs
What are the criterion used for impaired renal function?
Narrow range drugs
Drugs that are dependent on renal elimination
What are narrow range, renally eliminated drugs?
Digoxin (patients with renal dysfunction
Lithium (used in bipolar disorder and lots of attention to renal function must be paid)
Hypoglycaemics (insulin is substantially removed by kidneys in a complex manner)
Methotrexate (an anticancer drug)