Integrated Clinical Correlation Flashcards Preview

Molecules to Cells > Integrated Clinical Correlation > Flashcards

Flashcards in Integrated Clinical Correlation Deck (9)
Loading flashcards...
1

What causes albinism?

Defect in melanin production

2

What is a common mutation/problem in patients with Xeroderma Pigmentosum?

Nucleotide excision repair

3

What areXP patients at risk for?

Very high risk: Basal cell and squamous cell carcinoma

High risk: melanoma

4

What other cancers are XP patients at risk for?

Oropharyngeal squamous cell carcinoma
Ocular
CNS
Colorectal
Lung
Bladder
Prostate
Ovarian

5

What are carcinogens for XP patients to avoid?

Tobacco
Alcohol
HPV
Processed meet
Occupational (dyes, etc)

6

Secondary symptoms of XP?

Corneal clouding and ulceration
Neurological degeneration

7

Most XP patients live beyond age ___.

20

8

What is anticipation?

Earlier onset

9

Does Dyskeratosis congenita (DK) show anticipation?

Yes