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Flashcards in Stem Cells Deck (7)
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1

What does the inner cell mass (ICM) differentiate into?

Endoderm
Mesoderm
Ectoderm

2

At what day(s) is the embryo then considered a blastocyst?

Day 5-6

3

Can cells reverse to a pluripotent stem cell after differentiation?

Yes! Called induced pluripotent stem cells (iPs)

4

What do megakaryocytes produce?

Platelets

5

How do megakaryocytes generate platelets?

SDF1 and FGF4 chemokines promote megakaryocyte adhesion

Endothelial cells are sinusoidal: Proplatelets are extended into the vasculature through gaps

Shear forces cause the distal tip of the proplatelet to bleb off into circulation -> fully realized platelet

6

The poorer a country is, the _____ likely people are to donate blood.

LESS

7

High F leads to _____ severe sickle cell disease

less severe