Integrative MSK Flashcards

(48 cards)

1
Q

MA woman, progressive weakness

problems rising from chair
dec strength in proximal LE bilateerally

CK is elevated

dx is ___/____
mechanism is ___ inflammation of muscle

A

polymyositis/dermatomyositis

immune mediated

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2
Q

elderly woman, progressive bilateral knee pain

no redness/swelling

hypertrophy over DIP/PIP, crepitus

dx is ___

A

osteoporosis

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3
Q

YAW, pain/swelling in wrists/knuckles/fingers

worse in AM
swelling in multiple joints

lump on extensor surfaces
no rash/ulcers

dx is ____
early antibody is ____

A

RA

anti-CCP

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4
Q

MA woman, dysphagia of solids/liquids

skin on hands/fingers is tighter, sensitive to cold weather

nodules on forearms

dx is ____
antibody is ____

A

CREST

anti-centromere

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5
Q

YA woman, diffuse joint pain, fatigue/myalgia, fever

rash on face, pleurisy

dx is ____

antibodies include __/___

A

SLE

ANA/ani DS DNA

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6
Q

MA woman w weakness, rash on eyelids, difficulty swallowing

dec strength in proximal muscles, purple rash on eyelids/knuckles

CK is inc

dx is ___
antibodies include /__/

A

dermatomyositis

anti-Jo1/anti SRP/anti Mi2

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7
Q

ma woman w dry, itchy eyes, dry mouth, ulcerated corneas

dx is ___
ab present ____

A

sjogrens

anti-Ro./La

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8
Q

elderly man, fatigue and low grade fevers

hip/shoulder pain, tenderness over trapezius/deltoid/trochanter

strength is ___
___is inc

dx is _____

A

normal
ESR

polymyalgia rheumatica

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9
Q

Arthralgia, photosensitivity, serositis, rash, cytopenias

dx is ____
sensitive Ab ___
specific ab for lupus nephritis __/___

A

SLE
ANA
anti-DS DNA, anti-Smith ab

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10
Q

AM stiffness, symmetric, small joints of hand/feet, sub q nodules, joint erosions

dx is ___

A

RA

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11
Q

dry eyes/mouth

dx is ___

ab nclude __/___

may be positive for __/___

A

sjogrens

anti SSA (Ro) or anti SSb (la)

ANA, RF

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12
Q

YA male, low back pain, worse in AM

bilateral, forward bend, tender in SI joints, cannot touch toes
erosions in SI joint

dx is ___

A

AS

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13
Q

painful, swollen, knee

high fever, effusion, red

inc WBC in arthrocentesis, no crystals

dx is _____
causative org is probably __
do __ to dx

A

septic arthritis
staph aureus
arthrocentesis

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14
Q

YA woman, wrist/knee swelling, migratory pains

effusion in knee, papules on lower extremities

scant mucoid discharge from pelvis

dx is ____
causative organism is ___

A

gonococcal arhritis

n gonorhea

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15
Q

MA man, swelling in ankle

red, warm, swollen, negatively birefringent crystals

dx is ___

A

gout

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16
Q

Elderly male, knee pain/sweling

xray shows chondrocalcinosis

dx is ____
may be associated w __/__
crystals are __
___ birefringent, __ in parallel

A

pseudogout

Hemochromatosis, hyperPTH
rhomboid
+, blue

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17
Q

tx acute gout w __ or __

chronic w ___ such as __

A

NSAIDs, colchicine

XO inhibitor, allopurinol

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18
Q

conjunctivitis, urethritis, uveitis

dx is ___

causative orgs
S
Y
C
C
S
A

reactive arthritis

shigella
yersinia
campyl
chlamydia
salmonella
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19
Q

sausage shaped digits, arthritis, scaly rash on limbs

dx is __

A

psoriatic arthritis

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20
Q

popping sensation in knee, improved w ice/NSAIDs

medial joint line is tender
positive ___

dx is ___

A

McMurray

meniscal tear

21
Q

MA man, shoulder pain, worse when lifting arm overhead

TTP, pain w abduction, can lower arm smoothly

dx is ____
if could not lower arm slowly, dx is ___

A

rotator cuff tendonitis

rotator cuff tear

22
Q

immediate knee swelling, excess medial rotation to planted foot

dx is ____

23
Q

valgus stresss

__ injury

varus stress

__ injury

24
Q

hyperextension w knee pain

dx is ___

25
younger than 45, knee pain walking down steps pain at rest when knee flexed dx is ____
patellofemoral pain syndrome
26
teenage, ___ tenderness dx is ___ aka
tibial tuberosity Osgood schlatter tibial tubercle apophysitis
27
roll ankle, damage to ___
anterior talofibular ligament
28
pain over distal radial styloid w repetitive use of thumb dx is ____ swelling/stenosis of ___ and ___ tendon sheaths at wrist
De quervian tenosynovitis abductor pollicus longus extensor polllicus brevis
29
punch a wall w hand pain dx is ___ fracture of ____
boxer fracture | metacarpal
30
forced dorsiflexion in elderly fx is ___ avulsion of ___ from shaft of ___
colles fx | styloid process, radius
31
hand/wrist fracture, w ulnar nerve involvement fx to __
hamate
32
fall on outstretched hand, pain in anatomic snuff box dx is ___
scaphoid fracture
33
distal humerus injury affects __
ulnar nerve
34
young boy, leg pain family hx of retinoblastoma elevation of periosteum dx is ___
osteosarcoma
35
young boy, trauma to arm good grow, poor dentition, skeletal fractures blue discoloration to sclera dx is ____ defect in ___
OI type 1 collagen
36
young boy, post URI resists RoM to hip labs are normal dx is ____
transient synovitis
37
young boy w limp for month limited internal rotation of hip, antalgic gait dx is ___ aka ___ tend to have ___ pain over __/___ dec hip __/___
legg calve perthe dx idiopathic avascular necrosis of femoral head short stature anterior thigh/knee internal rotation/abduction
38
SCFE displaced ___ anteriorly usually seen in ___ assc w ___ or ___ or ___ insidious hx of ___, localized to ___ no/minimal ____
femoral head obese, adolescent male hypoT, pseudohypoPTH, GH deficiency dull pain, anterior hip trauma
39
baby, dec hip abduction clunk on exam dx is ___
DDH
40
YA male, muscle aches/fever, ab pain, rash numbness over fingers, foot drop Hep B positive, inc creatinine, ESR dx is ____
polyarteritis nodosa
41
old man, dffuse bony pain worse in clavicles, legs bowed worse hearing ALP is inc, others normal dx is ___ disorganized ___
paget dz of bone | bony matrix
42
comp of bisphosphonate therapy
osteonecrosis of the jaw
43
young boy, weak pelvic girld, Gower's sign, prominent calves dx is __ w deleted dystrophin gene dx is ___ w mutated dystrophin gene usually presents ___/__
duchenne becker older/milder
44
young boy, tumor in diaphysis of long bones/pelvis/scapula/rib dx is ____ hisotology shows ___ xray w ___ translocation
ewing sarcoma blue cells onion skin 11, 22 EWS-FLI1
45
side effect of NSAID __ via ___ A U
AKI, constriction of AA AIN ulcer
46
SE of aspirin T H leading to ___ w anion gap ___
tinnitus | hyperventilation, RA, MA
47
muscle change w exercise type 1 is __, __ fibers abundant in __/___ used for ___ type 2 is __/__ fibers used for __/___ inc anaeorbic ___
slow, red mito/myoglobin endurance fast, white strnegth/speed glycolytic capacity
48
endurance athlete __ to __ transition resistance recruits/hypertrophies ____ fibers
fast, slow | type 2