Integumentary Flashcards
(39 cards)
The specialized accessory structures of the skin
Adnexae
Part of dispersed neuroendocrine system; cells of basal layer which act as mechanoreceptors and help regulate epidermal and adnexal function, tactile sensation in lower animals
Merkel’s cells
Increased thickness of stratum corneum
Hyperkaratosis
Normal loss of nuclei in keratinized cells
Orthokeratotic hyperkaratosis
Nuclei retained in keratinized cell
Parakeratotic hyperkaratosis
Increased number of cells in stratum spinosum
Acanthosis
Regular downward projections of epidermis
Psoriasiform hyperplasia
Upward projections of stratum spinosum towards surface
Papillated epidermal hyperplasia
Dysplasia in early stages of squamous cell carcinoma; or appearance which mimics early neoplasia
Pseudoepitheliomatous hyperplasia
Premature or abnormal keratinization of stratum spinosum
Dyskeratosis
Decreased number of cells
Hypoplasia
Decreased size of cells
Atrophy
Loss of cohesion between keratinocytes due to antibodies against desmosomes
Acantholysis
Fluid-filled cavities (vesicles < 5mm, bullae > 5mm)
Vesicles/bullae
Migration of RBC or leukocytes into epidermis
Exocytosis
Microabscesses; vesicles filled with inflammatory cells
Pustules
Dried exudate, not diagnostic but may contain diagnostic elements such as bacteria, fungi, etc
Crusts
Decreased pigmentation on hair
Leukotrichia
Decreased pigmentation in skin
Leukoderma
Increased fibrous tissue
Fibroplasias
Inherited abnormalities of collagen metabolism
Collagen dysplasia
Chronic response to UV light, abnormal elastin production
Solar elastosis
Dissolution of collagen fibers
Collagen lysis
A hard waxy deposit consisting of protein and polysaccharides that results from the degeneration of tissue
Amyloid