Inflammation and Repair

Question 1

The process of reaction of vascularized living tissue to injury is called?

Answer 1

Inflammation

Question 2

Process by which lost or necrotic cells are replaced by vital cells

Answer 2

Repair

Question 3

Replacement by cells of same type

Answer 3

Regeneration

Question 4

Replacement by connective tissue

Answer 4

Scarring/fibrosis

Question 5

Protein rich fluid, inflammatory cells, cellular products, and cell debris accumulation at the site of an inflammatory reaction

Answer 5

Exudates

Question 6

Cell migration along a concentration gradient of inflammatory mediator

Answer 6

Chemotaxis

Question 7

Random migration stimulated by a chemical mediator

Answer 7

Chemokinesis

Question 8

The protein rich fluid and inflammatory cells that accumulate in extracellular spaces as a result of an inflammatory reaction

Answer 8

Exudate

Question 9

Refers to elimination of the inflammatory stimulus and senescence and removal of inflammatory cells after active inflammation

Answer 9

Resolution

Question 10

Inflammation resulting from injurious stimuli that are persistent, often for weeks or months, leading to a predominantly proliferative, rather than exudative, reaction

Answer 10

Chronic inflammation

Question 11

An inflammatory process dominated by macrophages

Answer 11

Granulomatous inflammation

Question 12

A compact and organized collection of mononuclear inflammatory cells (macrophages, lymphocytes, and plasma cells) dominated by macrophages

Answer 12

Granuloma

Question 13

Organized and compact aggregate of MOs and/or epithelial cells with other inflammatory cells such as lymphocytes and plasma cells

Answer 13

Simple granuloma

Question 14

Granuloma with central necrosis and possibly calcification

Answer 14

Complex granuloma

Question 15

Process resulting in an increase of collagen in tissue

Answer 15

Fibrosis

Question 16

Highly organized fibrovascular tissue that often replaces necrotic debris and areas where poor regeneration occurs

Answer 16

Granulation tissue

Question 17

Cells that continue to multiply throughout life and replenish those lost due to normal turnover

Answer 17

Labile cells

Question 18

Cells with latent capacity to regenerate

Answer 18

Stable cells

Question 19

Cells with no capacity to regenerate additional cells

Answer 19

Permanent cells

Question 20

Potent growth factor produced by MOs, stromal fibroblasts, and to a lesser extent by epithelial cells in some tissues that is a potent inducer of epithelial proliferation and repair

Answer 20

Epidermal growth factor

Question 21

Growth factor produced by MOs, platelets, endothelial cells, smooth ms cells; stimulates smooth ms proliferation and fibrosis

Answer 21

Platelet derived growth factor

Question 22

Produced by MOs and other cells; potent inducer of endothelial cell proliferate and angiogenesis

Answer 22

Basic fibroblast growth factor

Question 23

Produced by MOs and other cells including smooth ms cells, fibroblasts, platelets, and some epithelial cells; promotor of fibrosis and inhibits epithelial regeneration

Answer 23

Transforming growth factor beta

Question 24

Highly potent angiogenesis factor produced by MOs, smooth ms cells, and epithelial cells in tissues; also produced by many malignant tumors and assists in neoplasm angiogenesis

Answer 24

Vascular endothelial growth factor

Question 25

Produced on MOs, monocytes, and fibroblasts with wide range of biological properties

Answer 25

Tumor necrosis factor alpha

Question 26

Replacement of fibrin and necrotic debris by granulation tissue

Answer 26

Organization

Question 27

Tough sheet of fibrin

Answer 27

Pseudomembrane

Question 28

Detachable fibrinous exudate

Answer 28

Croupous

Question 29

In contrast to croupous, the fibrinous exudate is firmly attached to the underlying surface and cannot be removed without tearing off a superficial layer of bleeding surface

Answer 29

Diptheritic

Question 30

Retains the shape of the structure from which it was molded

Answer 30

Fibrinous cast

Question 31

Pus in a confined area

Answer 31

Abscess

Question 32

Pus spread thinly throughout (or diffusely) without being walled off (subcutaneously and along fascial plane)

Answer 32

Phlegmon (cellulitis)

Question 33

Accumulation of pus in a body cavity

Answer 33

Empyema

Question 34

Abscess consists of inspissated pus surrounded by a thick fibrous capsule

Answer 34

Cold abscess/ chronic abscess

Question 35

Made or having become thickened in consistency

Answer 35

Inspissated