Intercalated discs connect cardiac muscle fibers into a functional syncytium Flashcards

(26 cards)

1
Q

describe cardiac muscle cells

A
striated
short
fat
branched
interconnected
use sliding filament mechanism
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2
Q

describe cardiac muscles in term of nucleus

A

contains one or at most two large, pale, centrally located nuclei

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3
Q

In contrast, the plasma membranes
of adjacent cardiac cells interlock like the ribs of two sheets of
corrugated cardboard at dark-staining junctions called

A

intercalated discs

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4
Q

Intercalated discs contain anchoring________ and__________

A

desmosomes

gap junctions

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5
Q

The ______ prevent adjacent cells from separating during contraction, and the _____ allow ions to pass from cell to cell transmitting current across the entire heart

A

desmosomes

gap junctions

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6
Q

Because gap junctions electrically couple cardiac cells, the myocardium behaves as a single coordinated unit, or

A

functional syncytium

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7
Q

why is it significant that cardiac cells have 25% to 35% mitochondria in comparison to skeletal muscle having 2%

A

it makes them highly resistant to fatigue which is important because the heart is working all the time and if stops you are dead :(

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8
Q

in contrast to skeletal muscle, the myofibrils of cardiac muscle cells vary greatly in ____ and _____ extensively, accommodating the abundant ______between them.

A

diameter
branch
mitochondria

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9
Q

The system for delivering Ca2+ is ____ elaborate in cardiac muscle cells. The cardiac sarcoplasrnic reticulum is ____ and ____ the large terminal cisterns seen in skeletal muscle. As a result, cardiac muscle fibers do not have ____. In addition, the
T tubules are ____ and ____ than in skeletal muscle.

A
less
simpler
lacks
triads
wider
fewer
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10
Q

Some cardiac muscle cells are ____ excitable

A

self

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11
Q

what are the 2 kinds of myocytes in the heart

A

contractile cardiac muscle cells

pacemaker cells

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12
Q

responsible for the heart’s pumping

activity

A

contractile cardiac muscle cells

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13
Q

certain locations in the heart contain special noncontractile cells, called ____ cells, that spontaneously depolarize.

A

pacemaker

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14
Q

what is the special property of the heart called in terms of self excitability

A

automaticity

autorhythmicity

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15
Q
Because heart cells are electrically
joined together by gap junctions, these
cells can initiate not only their own
\_\_\_\_\_-, but also that of the rest
of the \_\_\_\_
A

depolarization

heart

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16
Q

if you cut all of the nerves of the heart will it still beat

A

yes, because it requires no neutral input

17
Q

the heart contracts as a ____

18
Q

all fibers in the heart contract as a ____ or the heart ________

A

unit

doesn’t contract at all

19
Q

recruitment cannot happen in the heart

because it acts as a

A

single huge motor unit.

20
Q

The influx of Ca2+ from extracellular fluid triggers

A

Ca2+

release from the SR

21
Q

In cardiac muscle, depolarization opens _________ in the plasma membrane. These _______ Ca2+ channels allow entry of 10-20% of the Ca2+ needed for contraction. Once inside, this influx of
Ca2+ triggers Ca2+ -_____channels in the SR to release bursts of Ca2+ (“calcium sparks”) that account for the other _______ of the Ca2+ needed for contraction

A

special Ca2+ channels
slow
sensitive
80-90%

22
Q

Tetanic contractions ______ occur in cardiac muscles

23
Q

If the heart were to contract tetanically, it would be ___________-, and so would be _____ as a pump

A

unable to relax and fill

useless

24
Q

The absolute refractory period in the heart is nearly ______________, which prevents ________ contractions.

A

as long as the contraction itself

tetanic

25
which type of respiration does the heart depend on
aerobic
26
Consequently, the real danger of an inadequate blood supply to the myocardium is not lack of nutrients, but lack of
oxygen