Interleukins Flashcards
(36 cards)
IL-1 Source
Macrophage
Lymphocytes
endothelium
fibroblasts
astrocytes
IL 1 target cell
T cells
B cells
macrophages
endothelium
tissue cells
IL- 1 effect
Lymphocyte activation
leukocyte endothelial adhesion
fever
regulates sleep
IL 2 source
T cells
IL 2 target cell
T cells
IL 2 effect
T cell growth factor
IL 3 source
T cells
IL 3 target
bone marrow cells
IL 3 function
stimulates bone marrow growth
IL 4 source
T cells
IL 4 target
B and T cells
IL 4 effect
B cell growth factor
IL 5 source
T cells
IL 5 target
B cells
IL 5 effect
B cell growth factor
IL 6 source
T and B cells
macrophages
fibroblasts
IL 6 target cells
B cells and hepatocytes
IL 6 effect
B cell differentiation and synthesis of acute phase reactants
IL 7 source
lymphocytes
IL 7 target
B and T cells
IL 7 stimulates proliferation of immature cells
IL 8 source
T cells
macrophages
IL 8 target
granulocytes
endothelium
IL 8 effect
stimulates the activity of neutrophils
acts as chemotaxin
inhibitor of endothelial cell leukocyte adhesion
