Intro Lectures Flashcards by Ben Leon

Q

Anterograde amnesia?
Axon Hillock?
Cortex made of?
Grey matter? (4)
White matter? (2)
Role of hippocampus?
Commissure vs. decussation?
Afferent? Efferent of neuron?
Genes –> ? –> Proteins –> Pathway –> ? (4)

A

Now new memories
Axon to soma
Grey matter
Cell bodies, dendrites, cortex brain, inner spinal cord
Inner brain, outer spinal cord
Facts
Crosses midline to mirror image
Dendrites to soma; axon
Expression; synapse; neuron; circuit; behavior

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Q

Cajal: Doctrine?
Sherrington: Contributed?
Hebb: Contribution?
Prominant nuceloulus makes?
Chromatin spread why?
4 things that are grey matter?

A

Neuron is functional component of info
Synapses based on integration
Patterns lead to changed circuits
ribosome
Most genetic material used
Nucleus, ganglion, body, cortex

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Q

Role of astrocytes? (3)
Microglia: Migrate?
Oligo myelinate?
Schwann myelinate?
Nissl substance?
Pet scan works how?
fMRI?
How do astrocytes effect blood flow? (7)

A

Take up k+ and NT; end feet around vessels; glial scar
Yes
Multiple axons; CNS
1 Axon; PNS
Rough ER
Labeled water or glucose moves
Increased BF = Increased activity
Glu taken up; release IC arach. acid; P450 converts it to EET; EET acts on arteriole; hyperpol. art.; lower tone; dilation

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Q

EPSP?
IPSP?
Coupling?
Brain activity with EM prop? (3)
Hemodynamic prop? (3)
EEG?
MEG?
fMRI?
PET?

A

Excit. post syn potential (towards threshold)
Inhib. “ “; away from potential
Astrocytes match blood supply to activity
EEG, EMG, MEG
PET, SPECT, fMRI
Bulk electric from scalp
Mag fields from currents
OxyHb = dimag., no distortion
Readiolabeled glucose

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Q

Trace venous back from somatosensory? (5)
Anterior cerebral gets? MC?
How does CSF return to blood?
Ependymal cell locations? Junctions?
Plasma ionic same as CSF?
How much made per day?
Comm. hydrocephalus?
Non- comm. hydroceph.?

A

Superior saggital; confluence; transverse; sigmoid; JV
Medial/ anterior; Lateral
Arachnoid granulations lining dural sinuses
Ventricles (leaky); choroid (tight)
No; doesn’t change as freely
500 ml
CSF to sub arachnoid space, not resorbed
CSF cannot make it to sub arachnoid space due to obstructed flow

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Q

Electrical synapse: Type of junction? Direction? Excitatory? Mutation connexin? Amplified?
Chemical synapse sequence? (9); cyto continuity? Direction?
Quantum hypothesis?
SNARE complex: Synaptotagin? Synaptobrevin? SNAP 25 (2x) and syntaxin? Unlocks SNARE? Makes vessicles?
Botox? Tetanus?
ACHr permeable to?
Nicotinic type? Muscarinic type?

A

Gap; bi; only; CMT; no
Basic AP at NMJ; no; uni
1 vessicle = 10k AcH
Ca2+ sensor; binds syntaxin; both presynaptic membrane; NSF; clatherin
Clips snares; clips inhibitory snares
cations
NMJ, ionotropic; ANS SM metabotropic

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Q

CNS glutamate NT: Need multiple what?
Noise gates do what?
Spatial summation?
Temporal summation?
NMDA: In channel? 5 steps? Called?
MEPPs?
EPPs?

A

Excitatory transmissions
AND; get rid of pesky outputs
Multiple different at same time
Multiple in a row
Mg; AP, Mg Leaves, calcium in, increase post sym receptor density (AMPA receptors dock); coincidence receptor
Mini end plate potentials; no Ca needed
Nerve evoked; Ca needed

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