Intro to Bloodstream Infections Flashcards Preview

Week 65: Sepsis > Intro to Bloodstream Infections > Flashcards

Flashcards in Intro to Bloodstream Infections Deck (14)
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1

Primary vs secondary bloodstream infection

Primary: the organism in the blood cannot be identified as arising from any source
Secondary: the organism in the blood is secondary to an identified source of infection (more common)

2

Is bloodstream infection the same as sepsis?

NO!

3

Most common cause of
1. Community
2. Hospital
based sepsis

1. E coli
2. Coag negative staph

4

4 common contaminating organisms

Coag negative staph (but can be real infection if person has IV catheter, prosthetic valve/joint)
Propionibacterium acnes
Corynebacterium
Bacillus
Contaminants dont require treatment

5

3 organisms that are never contaminants

Staph aureus
Gram-negative bacilli
Yeast

6

Staph aureus investigations

Repeat 2 sets of blood cultures every 48 hours until the blood is cleared
Echo to look for endocarditis
Infectious disease consult

7

Strep pneumo treatment

Penicillin, ampicillin and ceftriaxone usually susceptible
Ceftriaxone to be safe

8

How can you tell between strep pneumo and group A strep on a gram stain

Both gram +
Strep pneumo in pairs
GrA strep in chains (so is enterococcus)

9

Viridans group strep tx

Ceftriaxone
Drain the abscess if there is one

10

Where is
1. E faecalis
2. E faecium
more common?

1. Community
2. Hospital

11

Tx for
1. E faecalis
2. E faecium
And what 3 things are ineffective against enterococcus?

1. ampicillin, pip=tazo, imipenem
2. linezolif
Cephalosporins, meropenem, and ertapenem are ineffective

12

Examples of gram - bacilli

E coli
Klebsiella
Proteus
Enterobacter
Serratia
Pseudomonas
Bacteroides

13

Empiric tx for pseudomonas

Local antibiogram is KEY
Pip-tazo, meropenem, imipenem, or ceftazidime

14

Candida treatment

Micafungin empirically
Usually can switch to fluconazole