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Flashcards in Intro to Immunology Deck (20):
1

Innate Immunity (recognition mechanisms)

rapid response, fixed, limited number of specificities, constant during response, initiates the adaptive response

common effector mechanisms for the destruction of pathogens

2

Adaptive Immunity (recognition mechanisms)

slow response, variable, numerous highly specific specificities, improve during response

common effector mechanisms for the destruction of pathogens

3

Innate immunity consists of

barriers (skin), phagocytes (endocytose bacteria), complement (serum protein for innate recognition)

4

opsonin

something that increases the pahgocytosis of an object by binding to the object

5

complement

group of serum proteins involved in innate and adaptive immunity, important in inflammation, clearing out bacteria

6

antigen

molecule recognized by antibody or T-cell receptor

7

CD3

mature T-cells

8

CD28

recognition of presenting cells

9

CD40

co-stimulatory molecule

10

CD 40L

ligand for CD-40

11

CD25

IL-2 receptor (high affinity)

12

eosinophil

granulocyte, kills antibody coated parasites through release of granule contents

13

dendritic cell

basophilic cell, activates T cells and initiates adaptive immune response

14

mast cell

basophilic cell, expulsion of parasites from body through release of granules containing histamine and other active agents

15

monocyte

mononuclear phagocytes, circulating precursor cell to macrophage

16

macrophage

mononuclear phagocytes, phagocytosis and killing of microorganisms, activation of T cells and initiation of immune response

17

lymphocytes

production of antibodies (B cells) or cytotoxic and helper functions (T cells)

18

natural killer cells

lymphocyte, kills cells infected with certain viruses

19

neutrophil

lymphocyte, phagocytosis and killing of microorganisms

20

tissues with resident macrophage

liver, skin, connective tissue, brain, bone, joints, lungs