Introduction Flashcards

0
Q

Jumping genes

A

Transposons

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1
Q

Obligate intracellular but acellular parasites of plants, naked RNA, no human diseases

A

Viroids

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2
Q

Appearance of vacuolated neurons with loss of function and the lack of an immune response or inflammation

A

Spongiform encephalopathies

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3
Q

Smallest bacteria

A

Mycoplasma sp

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4
Q

Largest bacteria

A

Thiomargarita namibiensis

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5
Q

All have a cell wall composed of peptidoglycan except

A

Mycoplasma

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7
Q

Outer membrane of gram negative bacteria contains

A

Endotoxin/LPS

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8
Q

Procedure in Gram staining

A

Primary Stain - Violet
Mordant - Iodine
Decolorizing Agent - Acetone
Counterstain - Safranin

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9
Q

Culture for Mycobacteria

A

Acid Fast Stain

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10
Q

Culture for Spirochetes

A

Dark field Microscopy

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11
Q

Culture for Legionella

A

Silver Stain

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12
Q

Culture for Chlamydia and Ricketssia

A

Gram/Tissue Stain

Inclusion bodies

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13
Q

Clostridium perfringens

A

Egg yolk

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14
Q

Corynebacterium diphtheriae

A

Tellurite

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15
Q

Group D Strep

A

Bile esculin

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16
Q

Staphylococci

A

Mannitol salts

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17
Q

N meningitidis

N gonorrhoea from sterile sites

A

Chocolate

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18
Q

N gonorrhea from sterile sites

A

Thayer Martin

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19
Q

H influenza

A

Chocolate + Factor V and X

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20
Q

Mycobacterium tuberculosis

A

Lowenstein Jonsen

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21
Q

Vibrio cholerae

A

Thiosulfate Citrate Bile Salts TCBS

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22
Q

Bordetella pertussis

A

Bordet Gengou

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23
Q

Legionella pneumophilia

A

Charcoal yeast extract

24
Q

Campylobacter, Helicobacter

A

Skirrows, Campy

25
Borrelia burgdorferi
Barbour Stoenner Kelly
26
Mycoplasma pneumoniae
Eaton
27
Pseudomonas aeroginosa
Cetrimide
28
Unique to gram positive organisms, for antigenic deteminant
Techoic acid
29
All gram positive bacteria have NO endotoxin except
Listeria monocytogenes
30
Completely dependent on oxygen for ATP generation
Obligate aerobes
31
Use fermentation but can tolerate low amounts of oxygen
Microaerophiles
32
Utilize oxygen if it is present, but can use fermentation in its absence
Facultative anaerobe
33
Exclusively anaerobic, but insensitive to the presence of oxygen
Aerotolerant anaerobes
34
Cannot grow in the presence of oxygen because they lack the three important enzymes
Obligate anaerobes
35
Degree of organism pahogenecity
Virulence
36
Examples of Obligate Aerobes (9)
``` Nocardia Neisseria Pseudomonas Mycobacteria Bordetella Brucella B cereus Legionella Leptospira ```
37
Examples of Obligate Anaerobes (3)
Actinomyces Bacteroides Clostridium
38
Examples of Facultative Anaerobe (4)
Streptococcus Spirochetes - Borrela, Treponema Campylobacter Helicobacter
39
Bacterial DNA is | Human nuclear DNA is
Circular | Linear
40
All bacteria capsules are composed of polysaccharide except
Bacillus anthracis
41
Spore has keratin like coat called
Dipicolinic acid
42
Enumerate the Three Spirochetes
Leptospira Treponema Borrelia
43
Toxic proteins produced by ceratin bacteria that are lethal for other bacteria
Bacteriocins
44
Aerotolerant anaerobes
Propionibacterium | Lactobacillus
45
Facultative anaerobes
``` Mycoplasma Staphylococcus Bacillus anthracis Listeria Corynebacterium ```
46
Occurs when normal flora occupy receptor sites preventing pathogen from binding
Colonization resistance
47
``` Normal flora in the Skin Nose Mouth Dental plaque Colon (2) Vagina (3) ```
``` Staph epidermidis Staph aureus Viridans strep Strep mutans Bacteroides E coli Lactobacillus acidophilus E coli Strep agalactiae ```
48
Bacteria with IgA Protease (4)
Strep pneumoniae H influenza Neisseria meningitidis Neisseria goborrhoeae
49
Destroys both neutropholic leukocytes and macrophages
Leukocidin | PV Leukocidin in Staph aureus
50
All exotoxins are heat labile except
Staphylococcal enterotoxin
51
Culture for Salmonella and Shigella
Xylose-Lysine-Deoxycholate XLD
52
Culture for Leptospira interrogans
Ellinghausen McCullough Johnson Harris EMJH/MPL1/Fletchers
53
Antibiotics that are excellent with or without inflammation (8)
``` Sulfonamides Chloramphenicol Trimethoprim Metronidazole Rifampin Isoniazid Fluconazole Flucytosine ```
54
Antiobiotics that are good only eit inflammation
``` Meropenem Cephalosporins Aztreonam Ciprofloxacin Vancomycin Imipenem + cilastatin Penicillins ```
55
Antibiotics that are minimal or not good even with inflammation
Aminoglycosides Tetracyclines Lincosamides Macrolides
56
Antibiotics that cannot pass even with inflammation
Polymixins 1st and 2nd Cephalosporins Amphotericin B
57
Largest medically important bacteria
Borrelia burgdorferi