INTRODUCTION TO BIOINFORMATICS

Question 1

With this, we can submit the discovered biological data and store and organize such data

Answer 1

Bioinformatics

Question 2

It is a field which uses computers to store and analyze molecular biological information

Answer 2

Bioinformatics

Question 3

It is about finding and interpreting biological data online.

Answer 3

Bioinformatics

Question 4

It is the application of tools of computation and analysis to the capture and interpretation of
biological data

Answer 4

Bioinformatics

Question 5

Give the 3 principal components of Bioinformatics

Answer 5

1. Creation of databases
2. The development of algorithms and statistics
3. The use of these tools for the analysis and interpretation of various types of biological data

Question 6

They are repository or like banks, this is where we store or gather biological information

Answer 6

Databases

Question 7

These are designed to collect, archive, visualize, or arrange the biological information

Answer 7

Databases

Question 8

It helps or enables the scientist in the retrieval of data that they will be needing for their research

Answer 8

Databases

Question 9

It serves as a benchmark in the ongoing discovery of the molecular basis for disease, and this is the groundwork for molecular diagnostics

Answer 9

Human genome project

Question 10

It is a branch of bioinformatics that study about RNA molecules in a living organisms

Answer 10

Transcriptomics

Question 11

In this branch of bioinformatics, the genomes of bacteria, viruses, fungi, or parasites are described within a specific environment

Answer 11

Microbiomics

Question 12

In this branch of bioinformatics, it involves the description of the chemical processes involving metabolites

Answer 12

Metabolomics

Question 13

In this branch of bioinformatics, it describes the sequences of the WHOLE genome of an organisms

Answer 13

Genomics

Question 14

In this branch of bioinformatics, it describes the entire complement of proteins in the entire organisms

Answer 14

Proteomics

Question 15

it is done in a computer instead of a real laboratory

Answer 15

In silico

Question 16

Protein Database in USA

Answer 16

RCSB PDB

Question 17

This databases contains original data in the form or primary sequence data or structural data as submitted by the scientific community

Answer 17

Primary Databases

Question 18

This database contain biomolecular data in its original form.

Answer 18

Primary databases

Question 19

This database contains information that has been processed and derived from the raw data available in primary database

Answer 19

Secondary database

Question 20

Contains data derived from the results of
analyzed primary data or from the raw data.

Answer 20

Secondary databases

Question 21

It is a way of rearranging sequences of DNA, RNA, or protein to identify regions of similarity

Answer 21

Sequence alignment

Question 22

It is the known sequence

Answer 22

reference sequence

Question 23

It is the unknown sequence

Answer 23

query sequence

Question 24

give the 2 types of sequence alignment

Answer 24

Pairwise and multiple

Question 25

Give the tools used in pairwise

Answer 25

EMBOSS Water and BLAST

Question 26

Give the tools used in Multiple Sequence alignment

Answer 26

MUSCLE, MAFFT, CLUSTAL Omega

Question 27

A type of pairwise sequence alignment that Matching the residues (bases or amino acids) of two sequences across their entire length

Answer 27

Global Aalignment

Question 28

it Matches the identical sequences from 5’ to 3’

Answer 28

Global Alignment

Question 29

The two sequences are treated as potentially equivalent

Answer 29

Global Alignment

Question 30

It represents gap, which means there is presence in the first sequence and the second has none

Answer 30

dash line

Question 31

it means the first sequence is identical/similar to second sequence

Answer 31

Straight line

Question 32

A type of pairwise sequence alignment that Matching of two sequences from regions which have more similarity with each other

Answer 32

Local Alignment

Question 33

In this type of pairwise sequence, the two sequences may or may not be related

Answer 33

Local Alignment

Question 34

True or False: In global alignment, the whole sequence is aligned, whereas in local alignment, only a portion/part is aligned.

Answer 34

True

Question 35

In EMBOSS WATER, dissimilar bases are indicated by?

Answer 35

dot

Question 36

It is the analysis of more than two sequences

Answer 36

Multiple Alignment Tools

Question 37

It is a multiple sequence alignment tool that is used to directly compare the sequences to one another

Answer 37

CLUISTAL OMEGA

Question 38

in clustal omega, same color in one column means?

Answer 38

Similar

Question 39

It is a multiple sequence alignment tool that arranges the sequences of DNA, RNA, or protein to identify regions of similarity

Answer 39

MUSCLE

Question 40

This tool is used to find regions of local similarity between sequences

Answer 40

BLAST (Basic Local Alignment Search Tool)

Question 41

It is used to compare the unknown sequence with the database

Answer 41

Blast

Question 42

nucleotide to nucleotide aligment

Answer 42

Blastn

Question 43

protein to protein alignment

Answer 43

Blastp