Introduction to Cytogenetics Flashcards

1
Q

the study of heredity and variation

A

Genetics

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2
Q

study of transmission of traits and biological information between generations

A

Heredity

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3
Q

unit of heredity & segment of DNA carrying information

A

Gene

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4
Q

3 categories of traits

A

Morphological
Physiological
Behavioral

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5
Q

3 primary sources of genetic variation

A

Mutations
Gene flow
Sex

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6
Q

Changes in DNA

A

Mutations

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7
Q

Movement of genes from one population to another

A

Gene flow

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8
Q

Introduces new genetic combination that leads to genetic shuffling

A

Sex

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9
Q

1st law of Classical Genetics

A

Law of Segregation

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10
Q

2nd law of Classical Genetics

A

Law of Independent Assortment

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11
Q

Law of Independent Assortment is based on?

A

Chromosomal Theory of Inheritance

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12
Q

5 Nitrogenous bases

A

Adenine
Guanine
Cytosine
Thymine
Uracil

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13
Q

DNA or RNA

Adenine pairs with Thymine and Cytosine with Guanine

A

DNA

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14
Q

DNA or RNA

Adenine pairs with Uracil and Cytosine with Guanine

A

RNA

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15
Q

Types of RNA

A

messenger RNA
transfer RNA
ribosomal RNA

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16
Q

Study about the changes in gene frequencies

A

Evolutionary Genetics

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17
Q

Living organisms may come from non-living material

A

Abiogenesis

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18
Q

Theory that organisms develop from mini versions of themselves

A

Preformation

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19
Q

He studied a cork and coined the term “cell”

A

Robert Hooke (1665)

20
Q

Discovered living organisms particularly the protozoa and bacteria from rainwater

A

Anton van Leuwenhoek (1674)

21
Q

Published The Origin of Species, which describes the theory of evolution by natural selection

A

Charles Darwin (1859)

22
Q

Published Experiments in Plant Hybridization

A

Gregor Mendel (1866)

23
Q

Isolated nucleic acid from pus cells

First to identify DNA as a distinct molecule and that the genetic material is located in the nucleus

A

Friedrich Miescher (1869)

24
Q

Proved that the genetic material is indeed located in the nucleus

A

Ernst Haeckel (1871)

25
Who are those that rediscovered Mendel's work
Carl Correns Hugo de Vries Erich von Tschermak (1902)
26
Discovered that alkaptonuria, a human disease, has a genetic basis
Archibald Garrod (1903)
27
Hypothesized the behavior of chromosomes during meiosis, thus leading to the discovery that genes are located on chromosomes
Walter Sutton (1903)
28
Coined the term "gene"
Wilhelm Johannsen
29
Discovered linkage between genes and coined the term "epistasis" and "genetics"
William Bateson (1904)
30
Who are those that discovered the science of genetic linkage and coined the term "epistasis"
Reginald Punnet William Bateson (1910)
31
describes the interaction between two diffferent traits
Epistasis
32
Proved that genes are located on the chromosomes and discovered XX and XY chromosomes
Thomas Hunt Morgan
33
Began the study of quantitative genetics by partitioning phenotypic variance into a genetic and an environmental component
R.A. Fisher (1918)
34
Showed that X-rays induce mutations
Herman J. Muller (1926)
35
Showed that DNA can transform bacteria, demonstrating that DNA is the hereditary material
Oswald Avery Colin Macleod Maclyn Mccarty (1944)
36
Determined the structure of the DNA molecule, which leads directly to knowledge of how it replicates
James Watson Francis Crick (1953)
37
Solved the genetic code, showing 3 DNA bases code for one amino acid
Marshall Nirenberg (1966)
38
An enzyme found in retroviruses, was discovered and was used in cloning genes
Reverse Transcriptase (1970)
39
1st to create a recombinant DNA molecule
Paul Berg (1972)
40
Combine DNA from two diferent species invitro, then transformed it into bacterial cells
Stanley Cohen Herbert Boyer (1972)
41
Introduced the process of sequencing the genome of a bacteriophage
Frederick Sanger (1977)
42
Invented the process called Polymerase Chain Reaction (PCR)
Kary Mullis (1983)
43
In this technique, a segment of the DNA is amplified until millions of copies are produced in just a short period of time
Polymerase Chain Reaction
44
They have successfully cloned Dolly the sheep
Ian Wilmut Keith Campbell (1996)
45
First mammal to be cloned from an adult cell
Dolly the sheep
46
Simply differences in genetic sequence
Variation