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The Holy Grail (Miscellaneous) > Investigations > Flashcards

Flashcards in Investigations Deck (45)
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1

Dermatophyte

Woods Lamp

2

Porphyria Cutanea Tarda

Woods Lamp

3

T1 Hypersensitivity

Take history
Specific IgE
Skin prick
Challenge test
Induce anaphylaxis- look for Serum mast cell tryptase

4

T4 Hypersensitivity

Patch Test

5

Pemphigus vulgaris

Tzanck smear

6

Pemphigus/ pemphigoid (blistering conditions)

Biopsy + direct immunofluorescence
Pemphigus- nikolsky's positive
Pemphigoid- nikolsky's negative

7

Temporal Arteritis

Temporal biopsy (be aware of skip lesions)
Raised ESR
Raised CRP

8

Soft tissue swelling

USS
MRI

9

Crystal arthropathies

Needle aspirate and bifringence
Negative crystals- Uric acid = gout
Positive crystals- Calcium pyrophosphate = pseudogout
Alizarin red stain- hydroxyapatite = Milwakee Shoulder

10

Saddle anesthesia

Urgent MRI <6hrs
Mandator PR

11

Suspected SLE

Urinalysis to rule out Lupus nephritis
Biopsy

12

Suspected polymyositis

Serum CK (always elevated, can be normal in dermatomyositis)
Muscle biopsy (CDT8 cells in polymyositis, CDT4 in dermatomyositis)
Electromyography (EMG)

13

Acromegaly

Screening serum IGF-1
Oral Glucose Tolerance test (OGTT) (normal <0.4micrograms)

14

Cushing's

Screening overnight dexamethasone suppression
2day 3mg/day dexamethasone suppression (normal <50)

15

Conn's

Renin: Aldosterone ratio- screening
Saline suppression test (failure to suppress Aldosterone by 50% from 2L)

16

GH Deficiency

Screening Serum IGF-1
Oral insulin tolerance (expect GH to increase)

17

T1DM

Antibodies: Anti GAD, Anti IA2
Hba1c : > or equal to 48
Random glucose: > or equal: 11.1
Fasting glucose: > 7

18

T2DM

Random glucose: > or equal: 11.1
Fasting glucose: > 7
OGTT: > or equal to 11.1 (in 2 hours)
Hba1c : > or equal to 48

19

Diabetes Insipidus

Water deprivation test (serum : urine osmolarity = 2:1)

20

Polycystic Ovarian Syndrome

Rotterdam criteria: 2/3 of:
- Evidence of PSO on USS
- Menstrual irregularities
- Evidence of increased androgens

21

Pyloric Stenosis

Abdominal USS

22

Malrotation

XR

23

Interssusception

USS (Target sign)

24

Bacterial keratitis

Corneal scrape

25

Endopthalmitis

Aqueous/Vitreous culture

26

Acanthamoeba

Microscopy/culture

27

Toxoplasma/Toxocara

Serology:
Toxoplasm- parasite
Toxocara- nematode

28

Corneal trauma

Siedel's test (fluorescein leakage)

29

Scleritis

Phenylephrine drops- blood vessels should show contriction

30

BPPV

Dix-Hallpike test