JAALASJuly 2016 Random

Question 1

The elevated plus maze is used to test for anxiety-like behavior or spatial memory?

Answer 1

anxiety-like behavior

Question 2

What behavior does the marble burying test measure

Answer 2

neophobia, anxiety and repetitive behavior

records the number of marbles buried in a specific amount of time

Question 3

How can ES cell contribution to offspring be assessed visually?

Answer 3

by coat color

Question 4

The AVMA guideline on euthanasia recommends that “___” species should not be present when individual animal euthanasia is performed

Answer 4

“sensitive” species

Question 5

A recent study concluded that mice exposed to euthanasia of other animals by CO2 or decaptiation did had no noticeable affect.

Answer 5

They did however respond to the noise of the guillotine, whether and animal was being euthanized or not.

Question 6

Genus and species of Deer mice

Answer 6

Peromyscus maniculatus

Question 7

Are deer mice nocturnal or diurnal?

Answer 7

nocturnal

Question 8

According to this recent study which substrate seems to be ideal for deer mice nest building?

Answer 8

brown crinkled paper

Question 9

What is the mechanism of action of alfaxalone

Answer 9

GABA receptor binderWh

Question 10

Describe myoclonic jerk

Answer 10

leg twitching behavior associated with administration of alfaxalone to mice
large amplitude rhythmic movement

Question 11

genus and species of the goat

Answer 11

Capra hircus

Question 12

T or F.

Compared to sheep goats are considered more sensitive to pain

Answer 12

T

Question 13

What is the mechanism of action of local anesthetics, such as lidocaine?

Answer 13

sodium channel inhibition, preventing nerve conduction in pain fiber (A,delta, c)

Question 14

This recent study concluded that CRI lidocaine improved analgesia with no cardiopulmonary effect in goats

Answer 14

T

Question 15

T or F

Cefovecin has similar pharmacokinetics in dogs and NHPs

Answer 15

F

They are vastly different and for that reason cefovecin is no recommended for use in NHPs

Question 16

T or F

Transdermal fentanyl solution has been approved for use in dogs

Answer 16

T

Question 17

Name the reversal agent for Fentanyl

Answer 17

Naloxone

a pure opiate antagonist

Question 18

To which receptor sites does Naloxone bind?

Answer 18

mu, kappa and delta, highest affinity for mu

Question 19

A recent publications suggest that transdermal fentanyl is not recommended for use in NHPs

Answer 19

T

Due to unreliable pharmacokinetics in NHPs (neither the patch nor solution were recommended)

Question 20

What is the most common method of collection of genetic material from mice for genotyping

Answer 20

tail biopsy

Question 21

t or f

A recent publication recommends the use of ice-cold ethanol prior to tail biopsy in mice 7-15d of age

Answer 21

T

Question 22

What is the acceptable displacement volume of CO2 to use for rodent anesthesia

Answer 22

10-30% per minute

Question 23

A recent publication demonstrated a lack of significant effects on physiological, behavioral or histological parameters whether the acceptable flow rate of 10-30% or a much higher chamber displacement rate was used

Answer 23

questioning whether the AVMA guideline rate or a much higher rate is more humane

Question 24

What is the likely contributor of ulcerative dermatitis in C57BL6 mice or those on a B6 background?

Answer 24

Th-1 driven immune response

Question 25

According to a recent article, what is the recommended treatment for ulcerative dermatitis?

Answer 25

nail trimming

Question 26

Genus species, family and order of guinea pig

Answer 26

Cavia porcellus, Caviidae, Rodentia

Question 27

T or F | Guinea pigs are born with their eyes open?

Answer 27

T

Question 28

What does the term paurangiotic refer to in the Guinea pig eye

Answer 28

blood vessels occur only near the optic disc

Question 29

Do guinea pigs have a third eyelid to protect the cornea?

Answer 29

no it is vestigial | Also GPs blink only 2-5times every 20 min! They have pronounced tear film stability

Question 30

What are the most common bacterial pathogens associated the conjunctivitis in the GP

Answer 30

Chlamoydophila psittaci and caviar

Question 31

T or F | Tritrichomonas muris is a highly transmissible agent that occurs in the GI tract of mice

Answer 31

T | typically it is non-pathogenic, but may cause disease in immunocompromised mice

Question 32

T or F | Ronidazole is an antiparasiticide that my be useful in controlling Tritrichomonas muris in mice

Answer 32

T

Question 33

What is the primary mechanism of action of isoflurane

Answer 33

activation of gamma-aminobutyric acid channels, which increases chloride permeability of neurons

Question 34

genus species of ferret

Answer 34

Mustela putorius furo

Question 35

genus species of Sooty mangabeys

Answer 35

Cercocebus tays

Question 36

T or F | HCT can affect the accuracy of hand-held glucometers in humans

Answer 36

T

Question 37

T or F | Handheld glucometers are less accurate in the state of hypoglycemia

Answer 37

T

Question 38

Does arterial or venus blood generally have higher glucose levels

Answer 38

Arterial

Question 39

A recent article concludes that human or veterinary hand held glucometers are likely more accurate in NHPs?

Answer 39

human | HCT, sampling site, physiologic state might also have an effect on glucose accuracy